The efficacy and tolerability of mirabegron, a β3 adrenoceptor agonist, in patients with symptoms of overactive bladder.

Author: CardozoLinda, KotesStephanie, ThiagamoorthyGanesh, ZacchèMartino

Paper Details 
Original Abstract of the Article :
Mirabegron, is the only β-3 adrenoreceptor (AR) agonist available for the treatment of overactive bladder (OAB). To assess the efficacy and tolerability of this novel drug therapy, two phase II and six phase III Astellas-sponsored trials have been conducted with over 10,500 adults with OAB recruited...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707426/

データ提供:米国国立医学図書館(NLM)

Mirabegron: A Novel Approach to Overactive Bladder

Overactive bladder (OAB) is a common condition that can significantly impact quality of life. This study examines the efficacy and tolerability of mirabegron, a β3 adrenoceptor agonist, as a novel treatment for OAB. By analyzing the results of two phase II and six phase III clinical trials, the authors demonstrate that mirabegron is as effective as most antimuscarinics in reducing symptoms of OAB. Furthermore, they find that mirabegron is well-tolerated, with a similar rate of adverse effects as placebo. This research highlights the potential of mirabegron as a safe and effective alternative treatment for patients with OAB.

A New Frontier in OAB Treatment: Mirabegron's Promise

The study demonstrates that mirabegron offers a valuable alternative treatment option for patients with OAB. It shows that mirabegron is effective in reducing OAB symptoms and is well-tolerated, even in patients who are unsuitable for antimuscarinics or have experienced adverse effects from them. This research is like a camel caravan venturing into uncharted territory, uncovering a new and promising path to treat OAB.

Empowering OAB Patients: A Choice for Improved Quality of Life

This research provides encouraging news for patients struggling with OAB. The availability of mirabegron, a safe and effective alternative to traditional treatments, offers a new pathway for improving quality of life and regaining control over bladder function. It's like a camel caravan, navigating the desert of OAB, providing relief and restoring harmony for those seeking a better quality of life.

Dr.Camel's Conclusion

This comprehensive analysis of mirabegron's efficacy and tolerability underscores its potential as a valuable treatment option for patients with OAB. It offers a promising alternative to traditional medications, providing a new path to improved bladder control and a better quality of life. This research is like a beacon of hope in the desert, guiding us towards a better future for OAB patients.

Date :
  1. Date Completed 2016-02-02
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

26834839

DOI: Digital Object Identifier

PMC4707426

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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