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Systematic review of antibiotic resistance in acne: an increasing topical and oral threat.

Author: DrénoBrigitte, EfthimiouJohn, WalshTimothy R

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Antibiotic resistance is growing, with over half of acne-causing bacteria now resistant to common topical antibiotics. To combat this, using benzoyl peroxide with a topical retinoid is recommended instead of topical antibiotics. Oral antibiotics are still used for moderate to severe acne, but only in combination with a topical retinoid, benzoyl peroxide, or both, and ideally for no more than 3 months. Long-term antibiotic use should include benzoyl peroxide to reduce resistance, and the risks and benefits should be carefully weighed. Developing non-antibiotic acne treatments is crucial to limit resistance.
Paper Details　
Original Abstract of the Article :
Topical and oral antibiotics are routinely used to treat acne. However, antibiotic resistance is increasing, with many countries reporting that more than 50% of Propionibacterium acnes strains are resistant to topical macrolides, making them less effective. We reviewed the current scientific literat...See full text at original site
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引用元：
https://doi.org/10.1016/S1473-3099(15)00527-7

データ提供：米国国立医学図書館（NLM）

Antibiotic Resistance in Acne: A Growing Concern

The world of [acne treatment] is facing a growing challenge: antibiotic resistance. This study explores the alarming trend of increasing resistance to topical and oral antibiotics in [Propionibacterium acnes], a bacterium implicated in acne. Like a desert sandstorm, antibiotic resistance threatens to erode the effectiveness of these treatments.

The study reviewed the current scientific literature to understand the prevalence and implications of antibiotic resistance in acne. It highlights the importance of using alternative therapies like [benzoyl peroxide] and [topical retinoids] to minimize the development of resistance. The authors emphasize the need for responsible antibiotic use, recommending a combination of treatments and limiting the duration of oral antibiotic therapy to a maximum of 3 months.

Finding Alternatives to Antibiotics

This research emphasizes the need to find new strategies to combat acne without relying solely on antibiotics. Alternative therapies can help prevent the spread of antibiotic resistance and ensure effective treatment for acne. It's like finding a new source of water in the desert – exploring alternative approaches can provide a sustainable solution.

Preventing the Sandstorm of Resistance

The increasing prevalence of antibiotic resistance in acne is a significant threat. By understanding the underlying mechanisms of resistance and exploring alternative treatments, we can prevent the development of a resistant strain. It's like building a protective wall around our oasis, safeguarding it from the encroachment of the desert sandstorm.

Dr. Camel's Conclusion

The study highlights the urgent need to develop and implement strategies to combat antibiotic resistance in acne. Finding effective alternatives and using antibiotics judiciously are crucial steps in preserving their efficacy and preventing further complications. It's a call to action to protect our therapeutic oasis from the encroaching sandstorm of antibiotic resistance.

Date :
  1. Date Completed 2016-07-29
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26852728

DOI: Digital Object Identifier

10.1016/S1473-3099(15)00527-7

SNS
PICO Info
in preparation
Languages

English

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