Comparison of the analgesic effect of intravenous acetaminophen with that of flurbiprofen axetil on post-breast surgery pain: a randomized controlled trial.

Author: HaraMarie, MiyamotoChisato, NonakaTakahiro, SugitaMichiko, YamamotoTatsuo

Paper Details 
Original Abstract of the Article :
Acetaminophen is known to be a relatively weak analgesic with fewer side effects than nonsteroidal anti-inflammatory drugs (NSAIDs). This study aimed to determine whether intravenous (iv) acetaminophen produces comparable analgesic effects to those of flurbiprofen (positive control drug), an intrave...See full text at original site
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引用元:
https://doi.org/10.1007/s00540-016-2150-0

データ提供:米国国立医学図書館(NLM)

The Race for Pain Relief: A Comparison of Acetaminophen and Flurbiprofen Axetil

Post-surgical pain is a common and often challenging experience for patients. Acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for pain management, but their relative effectiveness remains a topic of debate. This randomized controlled trial (RCT) investigates the analgesic effects of intravenous (IV) acetaminophen compared to flurbiprofen axetil, an IV NSAID, in patients undergoing breast surgery.

Navigating the Desert of Post-Surgical Pain

The study's findings suggest that IV acetaminophen may provide comparable analgesic effects to flurbiprofen axetil in patients undergoing partial mastectomies. While IV acetaminophen is known to be a weaker analgesic, this study demonstrates its potential for pain management in this specific surgical setting. The study also reports similar patient satisfaction ratings at discharge for both treatment groups.

A New Path in Pain Management: Navigating the Desert

The results of this RCT provide valuable insights into the potential of IV acetaminophen for post-surgical pain management. While further research is needed to confirm these findings and explore its effectiveness in other surgical contexts, this study suggests that IV acetaminophen may be a viable option for pain relief, particularly in patients who may have contraindications to NSAIDs. The study represents a significant step in the ongoing quest to develop effective and safe pain management strategies, offering a new path through the desert of post-surgical pain.

Dr. Camel's Conclusion

This RCT offers a refreshing oasis in the desert of pain management research, shedding light on the potential of IV acetaminophen for post-surgical pain relief. While further investigation is necessary to solidify its place in pain management protocols, the study provides hope for patients seeking effective and safe alternatives to traditional NSAIDs. This research underscores the ongoing commitment of researchers to improve pain management strategies, offering a brighter future for those navigating the challenging terrain of post-surgical pain.

Date :
  1. Date Completed 2017-02-09
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26882922

DOI: Digital Object Identifier

10.1007/s00540-016-2150-0

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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