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Effects of Testosterone Treatment in Older Men.

Author: , AntonStephen, Barrett-ConnorElizabeth, BasariaShehzad, BhasinShalender, CauleyJane A, CellaDavid, CifelliDenise, CrandallJill P, CunninghamGlenn R, DiemSusan J, DougarDarlene, EllenbergSusan S, EnsrudKristine E, FarrarJohn T, FluhartyLaura, GillThomas M, HouXiaoling, LandisJ Richard, LewisCora E, MatsumotoAlvin M, MohlerEmile R, MolitchMark E, PahorMarco, ParsonsJ Kellogg, ResnickSusan M, RosenRaymond C, SnyderPeter J, Stephens-ShieldsAlisa J, StorerThomas W, SwerdloffRonald S, WangChristina, WengerNanette K, ZeldowBret

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, N.I.H., IntramuralFunding provided by the NIH for research projects within the NIH.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

In symptomatic men aged 65 or older with moderately low testosterone levels, raising testosterone levels for 1 year to the mid-normal range had a moderate benefit for sexual function and some benefit for mood and depressive symptoms. There was no benefit for vitality or walking distance. The number of participants was too small to draw conclusions about the risks of testosterone treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Serum testosterone concentrations decrease as men age, but benefits of raising testosterone levels in older men have not been established. METHODS: We assigned 790 men 65 years of age or older with a serum testosterone concentration of less than 275 ng per deciliter and symptoms suggest...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/26886521

データ提供：米国国立医学図書館（NLM）

Effects of Testosterone Treatment in Older Men

In the vast desert of aging research, scientists are constantly exploring the impact of hormonal changes on human health and well-being. This study investigates the effects of testosterone treatment in older men, a topic as complex and nuanced as the shifting sands of time.

Testosterone Treatment: A Potential Oasis in the Desert of Aging

The authors conducted a large-scale clinical trial to assess the effects of testosterone treatment in men aged 65 years or older with low testosterone levels. The study found that testosterone treatment increased serum testosterone levels to the mid-normal range for younger men, leading to improvements in sexual function, mood, and depressive symptoms.

Navigating the Landscape of Hormone Replacement: A Journey Through the Male Body

The study highlights the complex interplay between hormones and aging. While testosterone treatment can offer potential benefits for some older men, it's important to carefully consider the potential risks and benefits before embarking on this treatment path. The study also emphasizes the need for further research to fully understand the long-term effects of testosterone replacement therapy in older men.

Health Implications and Lifestyle Applications: Embracing a Healthy Lifestyle

This research encourages us to approach aging with a holistic perspective, considering both hormonal changes and lifestyle factors. Maintaining a healthy lifestyle, including regular exercise, a balanced diet, and adequate sleep, can play a significant role in promoting overall well-being and mitigating the effects of aging.

Dr. Camel's Conclusion

This study reminds us that the desert of aging is a vast and intricate landscape. While testosterone treatment can offer potential benefits for some older men, it's crucial to approach this therapy with caution and a comprehensive understanding of the potential risks and benefits. Embracing a healthy lifestyle and consulting with a healthcare professional are essential for navigating the challenges of aging and maintaining a vibrant and fulfilling life.
Date :
  1. Date Completed 2016-03-01
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

26886521

DOI: Digital Object Identifier

NIHMS762892

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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