Anaplastic large cell lymphoma in paediatric and young adult patients.

Author: BrugièresLaurence, KennerLukas, LamantLaurence, TurnerSuzanne D

Paper Details 
Original Abstract of the Article :
Anaplastic large cell lymphoma (ALCL) is a heterogeneous disease of debateable origin that, in children, is largely anaplastic lymphoma kinase (ALK) positive with aberrant ALK activity induced following the formation of chromosomal translocations. Whilst the survival rates for this disease are relat...See full text at original site
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引用元:
https://doi.org/10.1111/bjh.13958

データ提供:米国国立医学図書館(NLM)

Anaplastic Large Cell Lymphoma: Navigating the Path to Recovery

Cancer is a complex and challenging disease, requiring a multifaceted approach to diagnosis and treatment. This study explores the characteristics and treatment options for anaplastic large cell lymphoma (ALCL), a rare and aggressive type of lymphoma. The authors provide a comprehensive overview of this disease, highlighting the importance of early detection, targeted therapies, and ongoing research.

A Diverse Landscape: Understanding ALCL

The authors describe the diverse nature of ALCL, highlighting its heterogeneous presentation and the role of ALK gene mutations in its pathogenesis. This research provides a valuable framework for understanding the complexities of ALCL, emphasizing the importance of personalized treatment strategies tailored to the specific characteristics of the disease. It's like navigating a vast and intricate desert, recognizing that each dune has its own unique shape and structure.

A Quest for Better Treatments: Exploring New Avenues

The authors discuss the challenges of treating ALCL, particularly the high relapse rates and the need for more effective therapies. They highlight the potential benefits of targeted therapies, including ALK inhibitors, and the ongoing research efforts to develop new and improved treatments. This underscores the importance of innovation and collaboration in the fight against cancer, just like a caravan of explorers seeking new routes and resources in a challenging desert environment.

Dr.Camel's Conclusion

This review provides a comprehensive overview of ALCL, highlighting the need for personalized treatment strategies and the importance of ongoing research to develop more effective therapies. It emphasizes the importance of collaboration and innovation in the fight against cancer, just like a group of camels working together to navigate a treacherous desert landscape.

Date :
  1. Date Completed 2017-04-28
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

26913827

DOI: Digital Object Identifier

10.1111/bjh.13958

Related Literature

SNS
PICO Info
in preparation
Languages

English

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