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A multicentre, randomized, single-blind, parallel-group study comparing the efficacy and tolerability of benzoyl peroxide 3%/clindamycin 1% with azelaic acid 20% in the topical treatment of mild-to-moderate acne vulgaris.

Author: HennigM, RessC, SchallerM, SebastianM, SeidelD

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Clinical Trial, Phase IVPost-marketing surveillance. Monitors long-term safety/efficacy after approval.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Benzoyl peroxide 3% and clindamycin 1% demonstrated greater efficacy than azelaic acid 20% in the treatment of mild-to-moderate acne vulgaris and had a positive tolerability and safety profile.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Mild-to-moderate acne vulgaris is treated with a range of mono- and combination therapies; however, clinical evidence is still required to optimize treatment recommendations. OBJECTIVE: To compare the efficacy, tolerability and safety of a combination of benzoyl peroxide 3% and clindamy...See full text at original site
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引用元：
https://doi.org/10.1111/jdv.13541

データ提供：米国国立医学図書館（NLM）

Benzoyl Peroxide/Clindamycin: A More Effective Treatment for Acne Vulgaris

Acne vulgaris is a common skin condition that affects many adolescents and young adults. This research compares the efficacy of two topical treatments for mild-to-moderate acne: benzoyl peroxide 3%/clindamycin 1% (BPO + CLN) and azelaic acid 20% (AzA). They conducted a randomized controlled trial involving patients with acne vulgaris, comparing the effects of these treatments on inflammatory lesions. They discovered that BPO + CLN was significantly more effective than AzA in reducing inflammatory lesions, and both treatments were generally well-tolerated.

BPO + CLN: A Clear Winner for Acne Treatment

This research suggests that BPO + CLN is a more effective treatment for mild-to-moderate acne than AzA. This finding provides a valuable tool for dermatologists to optimize treatment strategies for their patients with acne vulgaris.

BPO + CLN: A Key to Clearer Skin

This research offers a potential solution for those seeking to improve their acne. BPO + CLN shows promise as a more effective treatment option, potentially leading to clearer skin and improved self-esteem.

Dr.Camel's Conclusion

This research offers a refreshing oasis in the desert of acne treatments. BPO + CLN emerges as a more effective option, potentially leading to clearer skin and a boost in confidence.

Date :
  1. Date Completed 2017-04-26
  2. Date Revised 2017-04-26
Further Info :

Pubmed ID

26915831

DOI: Digital Object Identifier

10.1111/jdv.13541

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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