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Endocrine management of advanced breast cancer.

Author: MouridsenH T, RoseC

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Tamoxifen has become the standard first-line endocrine therapy for advanced breast cancer. Oophorectomy and aminoglutethimide or progestins are effective as second-line therapies. Combined endocrine therapy has not shown consistent benefit.
Paper Details　
Original Abstract of the Article :
Recent research has produced several new options for endocrine treatment of advanced breast cancer. Since one of the most intriguing characteristics of endocrine therapy is that new remissions are possible when subsequent endocrine modalities are used, it is important to evaluate their optimal seque...See full text at original site
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引用元：
https://doi.org/10.1159/000181344

データ提供：米国国立医学図書館（NLM）

Endocrine Management of Advanced Breast Cancer: A Journey Through Treatment Options

Advanced breast cancer is a challenging condition that requires comprehensive and individualized treatment. This study explores the evolving landscape of endocrine therapy for advanced breast cancer, providing a roadmap for navigating the diverse treatment options available. It's like exploring a vast desert, where different routes lead to different destinations, each with its own advantages and disadvantages.

A Comprehensive Approach to Treatment

The study highlights the importance of a sequential approach to endocrine therapy, starting with tamoxifen as the first-line treatment. This is like choosing a reliable camel for a long journey, one that can handle the initial stages of the desert trek. The authors also discuss the potential of oophorectomy, aminoglutethimide, and progestins as subsequent treatment options, depending on the patient's specific needs and response to therapy. This is like adapting the caravan's strategy based on the changing conditions of the desert landscape.

Navigating the Terrain of Endocrine Therapy

This study provides a valuable guide for clinicians and patients navigating the complex world of endocrine therapy for advanced breast cancer. It highlights the importance of individualized care, taking into account factors such as patient characteristics, disease stage, and response to treatment. This is like choosing the right tools and strategies for a successful journey through the desert. This research underscores the importance of ongoing research and development in the field of breast cancer treatment, seeking to improve outcomes and enhance patient quality of life.

Dr.Camel's Conclusion

This study provides a comprehensive overview of endocrine therapy for advanced breast cancer, emphasizing the importance of a sequential approach and individualized care. It highlights the various treatment options available, offering a roadmap for navigating this complex landscape. Just as a camel adapts its journey to the changing conditions of the desert, clinicians must remain flexible and responsive to the unique needs of their patients. This research represents a valuable contribution to the ongoing effort to improve the lives of those affected by breast cancer.

Date :
  1. Date Completed 1990-03-15
  2. Date Revised 2018-02-15
Further Info :

Pubmed ID

2693326

DOI: Digital Object Identifier

10.1159/000181344

Related Literature

Article Analysis
・Effective treatment of breast cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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