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Comparison of the effects of long-term pimobendan and benazepril administration in normal cats.

Author: MachidaNoboru, MiyagawaYuichi, TakemuraNaoyuki, TodaNoriko, TominagaYoshinori

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This blinded, randomized study investigated the potential cardiac effects of pimobendan and benazepril in healthy cats. Neither drug showed significant adverse cardiac effects or lesions, suggesting potential safety in cats. However, further research is needed to evaluate their effects in cats with heart disease.
Paper Details　
Original Abstract of the Article :
Pimobendan (PIMO) can cause adverse effects, such as mitral valve degeneration, in dogs; however, it is unclear whether these effects occur in cats. Therefore, we aimed to determine whether PIMO or benazepril produces adverse cardiac effects in healthy cats. This was a blinded, randomized, prospecti...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976264/

データ提供：米国国立医学図書館（NLM）

The Heart of the Matter: Pimobendan and Benazepril in Healthy Cats

Imagine a camel with a heart condition. What kind of medication would you give it? This study explores the effects of two common medications used to treat heart conditions in cats: pimobendan and benazepril. The researchers wanted to see if either drug could cause any unintended harm to a healthy feline heart, kind of like checking if a camel's hooves are strong enough for a long journey through the desert.

Navigating the Effects of Heart Medication in Cats

The study found that neither pimobendan nor benazepril appeared to cause any significant cardiac lesions in healthy cats. This provides reassurance for veterinarians and cat owners about the potential safety of these medications. It's like knowing that a camel's hooves are sturdy enough to handle the journey, allowing for a more confident approach to its well-being.

Safeguarding the Health of Feline Companions

This research provides valuable insights into the safety of pimobendan and benazepril in healthy cats. While further studies are needed to assess their effects in cats with heart disease, this study suggests that these medications may be suitable for treating heart conditions in cats without causing any adverse cardiac effects.

Dr. Camel's Conclusion

This study sheds light on the potential safety of two common medications used to treat heart conditions in cats. While further research is needed, this study suggests that these medications may be a valuable tool for veterinarians in caring for their feline patients.

Date :
  1. Date Completed 2017-05-25
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

26972332

DOI: Digital Object Identifier

PMC4976264

Related Literature

Article Analysis
・Effects of benazepril
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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