Intra-articular treatment of knee osteoarthritis: from anti-inflammatories to products of regenerative medicine.

Author: AngelosMathew G, GolzarianJafar, MaxwellJoshua Shane, RichardsMasters M, WengLihui

Paper Details 
Original Abstract of the Article :
Knee osteoarthritis (OA) is a debilitating condition that may ultimately require total knee arthroplasty (TKA). Non-operative treatments are bracing, oral analgesics, physical therapy, and intra-articular knee injection (IAKI). The objective of this paper is to provide a systematic literature review...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/26985986

データ提供:米国国立医学図書館(NLM)

A Journey Through Knee Osteoarthritis: From Anti-Inflammatories to Regenerative Medicine

Knee osteoarthritis (OA), a debilitating condition, is like a desert landscape, slowly eroding the cartilage in the knee joint, leading to pain, stiffness, and limited mobility. This research explores the current landscape of intra-articular knee injection (IAKI) treatments, ranging from traditional anti-inflammatory drugs to cutting-edge regenerative medicine approaches. It's like taking a guided tour through the desert, uncovering various strategies for managing knee OA, from basic hydration to advanced oasis restoration.

Navigating the Desert of Treatment Options

The researchers reviewed the evidence for various IAKI treatments, including corticosteroids, hyaluronic acid, and platelet-rich plasma. They found that while some treatments, like corticosteroids, can provide temporary relief, they don't address the underlying problem of cartilage degeneration. It's like finding a temporary waterhole in the desert but not a permanent solution. The authors suggest that regenerative medicine approaches, such as stem cell therapy and growth factor delivery, hold promise for repairing damaged cartilage and potentially slowing the progression of OA. It's like discovering a hidden spring in the desert, offering hope for restoring the damaged landscape.

A Desert Oasis for Knee Health

This review highlights the evolving landscape of knee OA treatment. While traditional IAKI treatments have their place, regenerative medicine is emerging as a potential game-changer, offering hope for long-term relief and potentially even reversing the damage caused by OA. It's like transitioning from a dusty desert path to a lush oasis, bringing new possibilities for managing this challenging condition.

Dr.Camel's Conclusion

This systematic review of intra-articular knee injection treatments for osteoarthritis provides a valuable overview of current options and potential future directions. While traditional treatments offer temporary relief, regenerative medicine offers promising solutions for long-term management and potentially even cartilage repair. Further research is needed to fully understand the efficacy and safety of these innovative approaches, paving the way for a brighter future for individuals living with knee osteoarthritis.

Date :
  1. Date Completed 2016-11-09
  2. Date Revised 2022-04-19
Further Info :

Pubmed ID

26985986

DOI: Digital Object Identifier

NIHMS794133

Related Literature

SNS
PICO Info
in preparation
Languages

English

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