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Colitis induced by sodium polystyrene sulfonate in sorbitol: A report of six cases.

Author: DhusUbal, JacobSheba S K, ParameswaranAshok, ParameswaranSarojini Ashok

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Kayexalate, used to treat hyperkalemia, can cause damage to the gastrointestinal tract, especially the colon. This study presents a characteristic pattern of injury associated with Kayexalate colitis, emphasizing the need for inclusion in the differential diagnosis of lower GI mucosal injury in patients with uremia and hyperkalemia.
Paper Details　
Original Abstract of the Article :
Drug-related injury has been noted in virtually all organ systems, and recognition of the patterns of injury associated with medication enables modification of treatment and reduces the morbidity associated with the side effects of drugs. With the large number of new drugs being developed, documenta...See full text at original site
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引用元：
https://doi.org/10.1007/s12664-016-0635-2

データ提供：米国国立医学図書館（NLM）

Colitis Induced by Sodium Polystyrene Sulfonate

This study investigates the occurrence of colitis, an inflammation of the colon, as an adverse effect of sodium polystyrene sulfonate (SPS), a medication used to treat hyperkalemia (high potassium levels in the blood). The researchers report a series of six cases where SPS administration was associated with colitis. They highlight the importance of recognizing this potential side effect, particularly in patients with uremia (excess urea in the blood) and hyperkalemia.

SPS-Associated Colitis: A Potential Side Effect

The study highlights the potential for sodium polystyrene sulfonate (SPS) to cause colitis, an inflammation of the colon. The researchers report a series of cases where SPS administration was associated with colitis, emphasizing the importance of recognizing this potential side effect, particularly in patients with uremia and hyperkalemia. This information is critical for healthcare providers to consider when prescribing SPS.

Managing Potassium Levels with Caution

Imagine a camel traversing a harsh desert landscape, encountering challenging terrain and potential hazards. Just as the camel needs to navigate these obstacles carefully, healthcare providers must carefully manage potassium levels in patients, considering the potential side effects of medications like SPS. This study underscores the importance of vigilant monitoring and the need to weigh the benefits and risks of SPS treatment.

Dr.Camel's Conclusion

This study highlights the potential for sodium polystyrene sulfonate (SPS) to cause colitis, an inflammation of the colon. The researchers report a series of cases where SPS administration was associated with colitis, emphasizing the importance of recognizing this potential side effect, particularly in patients with uremia and hyperkalemia. Healthcare providers should carefully consider the risks and benefits of SPS treatment and monitor patients closely for signs of colitis.
Date :
  1. Date Completed 2017-03-09
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

27033844

DOI: Digital Object Identifier

10.1007/s12664-016-0635-2

Related Literature

Article Analysis
・Side Effects of sodium polystyrene sulfonate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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