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[Cancers of the breast at metastatic high-risk: prediction of survival by steroidal receptors].
Author: ChauvergneJ, DavidM, DurandM, MauriacL, WafflartJ
Original Abstract of the Article :
From 1982 to 1985, 279 patients with locally advanced breast cancer have been treated with induction chemotherapy, adjusted loco-regional treatment (surgery and/or radiotherapy) and adjuvant chemotherapy with or without immunostimulation. Overall and relapse free survivals are better for tumors with...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2713513
データ提供:米国国立医学図書館(NLM)
Predicting Survival in Metastatic Breast Cancer
This research explores the challenging field of [breast cancer] and examines the potential of [steroidal receptors] as [prognostic markers] for [metastatic breast cancer]. The study analyzed data from [279 patients] with [locally advanced breast cancer] who received a combination of [induction chemotherapy, loco-regional treatment, and adjuvant chemotherapy]. Researchers aimed to identify factors that could predict [overall and relapse-free survival] in these patients.
The Prognostic Value of Estrogen and Progesterone Receptors
The study found that [tumors with estrogen and progesterone receptors (EPR)] were associated with [better overall and relapse-free survival rates]. This suggests that [the presence of EPR] may be a [favorable prognostic factor] for [metastatic breast cancer]. The researchers also explored the potential of [hormonotherapy] as a [treatment option] for patients with [EPR-positive tumors].
Potential for Personalized Treatment Approaches
This research highlights the importance of [identifying biomarkers] that can help predict [treatment response and survival] in [metastatic breast cancer]. It emphasizes the potential of [personalized medicine] to tailor treatment approaches based on [individual patient characteristics]. This may involve [targeting specific molecular pathways] involved in tumor growth and progression.
Dr. Camel's Conclusion
This research reminds us that the desert of cancer treatment is constantly evolving. By delving into the complexities of [tumor biology] and identifying [prognostic markers], we can navigate this challenging landscape with greater precision and effectiveness. The study provides valuable insights into the potential of [personalized medicine] to improve outcomes for patients with [metastatic breast cancer].
Date :
- Date Completed 1989-06-14
- Date Revised 2009-11-11
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