[Side effect management of tyrosine kinase inhibitors in urology : Hypertension].

Author: KeckB, LiebV, MeidenbauerN, SikicD

Paper Details 
Original Abstract of the Article :
Tyrosine kinase inhibitors like sunitinib, sorafenib, pazopanib or axintinib are regarded the standard of care in the systemic therapy of metastatic renal cell carcinoma. However, the many side effects associated with this therapy pose challenges for the treating physician and the patient. This revi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s00120-016-0089-2

データ提供:米国国立医学図書館(NLM)

Taming the Side Effects of Tyrosine Kinase Inhibitors

Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of metastatic renal cell carcinoma. These powerful drugs target specific proteins involved in tumor growth, but their effectiveness can be hampered by a range of side effects, notably hypertension. This research focuses on the management of hypertension caused by TKIs, providing a comprehensive overview of the classification and treatment of this common side effect.

Balancing the Scales: Effectiveness and Side Effects

The authors emphasize the importance of managing hypertension to optimize both treatment efficacy and patient compliance. The prevalence of hypertension among patients taking TKIs underscores the need for a vigilant approach to side effect management. Effective strategies for controlling hypertension, like lifestyle modifications and tailored medication regimens, can help patients experience the full benefits of TKI therapy without compromising their overall health.

Living with TKIs: Tips for Patient Management

It's crucial for patients taking TKIs to maintain close communication with their healthcare providers to manage hypertension and other potential side effects. A proactive approach to managing these challenges can help patients navigate TKI therapy with greater ease and improve their quality of life. Remember, patients are at the heart of the treatment process, and their voices matter.

Dr. Camel's Conclusion

Think of TKIs as a powerful desert wind, capable of blowing away the sands of cancer. But like a strong wind, TKIs can sometimes stir up a storm of side effects. Managing hypertension, like building a protective sand dune, ensures the benefits of TKI therapy can flourish.

Date :
  1. Date Completed 2017-05-10
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27146871

DOI: Digital Object Identifier

10.1007/s00120-016-0089-2

SNS
PICO Info
in preparation
Languages

German

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.