The safety of meperidine prescribing in older adults: A longitudinal population-based study.

Author: BugdenShawn, FalkJamie, FriesenKevin J

Paper Details 
Original Abstract of the Article :
Meperidine (pethidine) is an opioid analgesic that offers little advantage relative to other opioids and several disadvantages including limited potency, short duration of action, and the production of a neurotoxic metabolite (normeperidine) with a long half-life. Older adults are more sensitive to ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864911/

データ提供:米国国立医学図書館(NLM)

Meperidine: A Risky Ride in the Desert of Pain Management

Greetings, fellow travelers, Dr. Camel here, navigating the complex and often confusing world of pain management. This study explores the use of meperidine, an opioid analgesic, in older adults, a demographic that's like a delicate camel caravan traversing a harsh desert environment.

The study highlights the potential risks associated with meperidine use in older adults, including a higher sensitivity to its side effects and a slower metabolism, making it harder to clear the drug from the body. It's like a camel caravan carrying a heavy load in a treacherous desert, where the weight of the burden can lead to complications.

A Cautionary Tale for Older Adults

This study suggests that meperidine should be used with caution in older adults, as it can pose a greater risk than other opioid analgesics. It's like choosing a weary camel for a long journey, one that might not be able to handle the demands of the road. The study emphasizes the need for careful monitoring and dose adjustments in this population to minimize the risk of adverse effects.

Navigating the Desert of Pain

This study serves as a reminder that pain management in older adults is a complex and delicate process. It's crucial to carefully weigh the risks and benefits of each medication, just like choosing the right camel for a specific journey. As a researcher, I'm always concerned with finding safe and effective ways to manage pain, and this study highlights the need for individualized approaches, especially in vulnerable populations.

Dr. Camel's Conclusion

This study underscores the need for careful consideration when prescribing meperidine to older adults, highlighting the potential for adverse effects in this vulnerable population. It's a reminder that pain management is a complex process, requiring a nuanced approach to ensure the safety and well-being of our patients. As we continue to explore new and safer pain relief options, we can strive to create a more comfortable and secure journey for all.

Date :
  1. Date Completed 2016-10-19
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27170170

DOI: Digital Object Identifier

PMC4864911

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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