Paper Details 
Original Abstract of the Article :
OBJECTIVE To determine effects of glycopyrrolate administered IM on Schirmer tear test I (STT I) measurements in dogs. DESIGN Prospective clinical study. ANIMALS 13 client- and staff-owned dogs. PROCEDURES For both eyes of each dog, STT I measurements were recorded twice 20 minutes apart (at T1 and ...See full text at original site
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引用元:
https://doi.org/10.2460/javma.248.11.1262

データ提供:米国国立医学図書館(NLM)

Glycopyrrolate and Tear Production in Dogs

Oh, the wonders of canine ophthalmology! This study dives into the effect of glycopyrrolate, a medication commonly used to dry up secretions, on tear production in dogs. Researchers meticulously measured tear production using the Schirmer tear test in 13 dogs before and after receiving an intramuscular injection of glycopyrrolate. The results were clear as desert sands – glycopyrrolate significantly reduced tear production.

The Dry Desert of Canine Tear Production

The study revealed a significant decrease in tear production after glycopyrrolate administration, with a mean reduction of 67.4%. This reduction was transient, thankfully, and tear production returned to baseline levels within 24 hours. The researchers recommend the use of lacrimomimetics, medications that increase tear production, to address the temporary dry eye condition.

Keeping Canine Eyes Moist in the Desert

This research reminds us that even seemingly minor interventions can have significant effects on our furry friends. Veterinarians and dog owners should be aware of the potential for glycopyrrolate to cause dry eye in dogs. With a little bit of planning and proactive care, we can help our canine companions navigate the desert of dry eyes with ease.

Dr.Camel's Conclusion

This study highlights the importance of understanding the impact of medications on various bodily functions, even in our canine companions. By recognizing the potential for glycopyrrolate to affect tear production, veterinarians can make informed decisions about treatment and ensure the continued well-being of their patients.

Date :
  1. Date Completed 2017-03-08
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27172342

DOI: Digital Object Identifier

10.2460/javma.248.11.1262

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SNS
PICO Info
in preparation
Languages

English

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