Effectiveness and safety of topical tacrolimus monotherapy for repigmentation in vitiligo: a comprehensive literature review.

Author: OrangesCarlo Maria, SistiAndrea, SistiGiovanni

Paper Details 
Original Abstract of the Article :
Thus far, several small studies and case reports on the use of topical immunomodulators in vitiligo have been published. We undertook a comprehensive literature review, searching for studies evaluating clinical response to tacrolimus topical therapy for vitiligo. A search was performed on PubMed/Med...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861566/

データ提供:米国国立医学図書館(NLM)

Topical Tacrolimus: A Potential Remedy for Vitiligo

This study reviews the existing literature on the use of topical tacrolimus, an immunosuppressant medication, for the treatment of vitiligo, a skin condition characterized by depigmentation. The researchers analyzed data from 29 studies involving 709 patients who received topical tacrolimus monotherapy. They found that tacrolimus was generally effective in promoting repigmentation, with the best results observed on lesions of the face. The treatment was well-tolerated, with only localized side effects reported. The study highlights the potential benefits of topical tacrolimus for vitiligo but emphasizes the need for larger and more standardized clinical trials.

Tackling Vitiligo: A New Avenue for Treatment

The study's findings suggest that topical tacrolimus can be a valuable tool in the treatment of vitiligo, offering a potential alternative to existing therapies. However, the need for further research underscores the importance of ongoing investigation and development in this area.

Finding Relief in the Desert of Vitiligo

Imagine a desert landscape where the lack of pigment can be a source of distress. This study explores the potential of topical tacrolimus as a restorative force, helping to restore color and improve the quality of life for people with vitiligo. The findings offer hope for new and effective treatments for this challenging skin condition.

Dr.Camel's Conclusion

This comprehensive literature review sheds light on the potential of topical tacrolimus as a treatment option for vitiligo. While the findings are encouraging, further research is crucial to validate its efficacy and safety in larger populations. This research underscores the ongoing efforts to develop new and effective therapies for vitiligo and improve the lives of people affected by this condition.

Date :
  1. Date Completed 2017-03-22
  2. Date Revised 2019-11-20
Further Info :

Pubmed ID

27192518

DOI: Digital Object Identifier

PMC4861566

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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