Paper Details

  1. Home
  2. Paper Details

Ciclesonide: A Pro-Soft Drug Approach for Mitigation of Side Effects of Inhaled Corticosteroids.

Author: DerendorfHartmut, MukkerJatinder Kaur, SinghRavi Shankar Prasad

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Ciclesonide, a pro-soft drug, is an inhaled corticosteroid used for treating asthma. It is converted to its active metabolite in the lungs, which has a higher anti-inflammatory effect and fewer systemic side effects than ciclesonide. Ciclesonide has favorable pharmacokinetic and pharmacodynamic properties, leading to high pulmonary deposition, distribution, and long residence time. Clinical studies support its safety and efficacy in mild, moderate, and severe asthma patients.
Paper Details　
Original Abstract of the Article :
Inhaled corticosteroids are used as one of the first-line drug therapy in patients with asthma. However, their long-term use is associated with various oropharyngeal and systemic side and adverse effects. Design of pro-soft drug is one of the strategies, which was adopted in the design of ciclesonid...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.xphs.2016.05.004

データ提供：米国国立医学図書館（NLM）

Ciclesonide: A Desert Oasis of Inhaled Corticosteroid Treatment

The desert of respiratory health can be a challenging terrain, with many obstacles to overcome. This study, like a team of researchers seeking a solution for asthma, explores the potential of ciclesonide, a pro-soft drug, for mitigating the side effects of inhaled corticosteroids. The researchers, like skilled pharmacists, delve into the unique properties of this medication, highlighting its conversion to an active metabolite in the lungs, while minimizing systemic exposure. This research suggests that ciclesonide, like a well-placed oasis in the desert of asthma treatment, offers a more targeted approach with reduced side effects. This study provides valuable insights into the development of pro-soft drugs and their potential for improving treatment outcomes while minimizing adverse effects.

Ciclesonide: A Potential Oasis for Asthma Treatment

This study suggests that ciclesonide could offer a valuable therapeutic option for individuals with asthma, providing targeted relief with reduced side effects. This research, like discovering a hidden oasis in a vast desert, provides hope for finding more effective and safer treatment strategies for this chronic respiratory condition.

A Camel's Perspective on Ciclesonide

I've seen how the desert wind can irritate the respiratory system, making it difficult to breathe. This study reminds me that finding the right treatment for respiratory conditions can be like finding a source of clean water in the desert. Ciclesonide, like a hidden oasis, offers a promising solution with minimal side effects. It's like a refreshing drink that soothes the throat and eases the lungs!

Dr.Camel's Conclusion

This research highlights the potential of ciclesonide as a pro-soft drug for mitigating the side effects of inhaled corticosteroids, offering a more targeted approach to asthma treatment. It underscores the importance of developing innovative strategies for improving the effectiveness and safety of medications.

Date :
  1. Date Completed 2017-11-21
  2. Date Revised 2019-01-04
Further Info :

Pubmed ID

27339407

DOI: Digital Object Identifier

10.1016/j.xphs.2016.05.004

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.