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Impact of Food Components on in vitro Calcitonin Gene-Related Peptide Secretion-A Potential Mechanism for Dietary Influence on Migraine.

Author: BourguignonJulia, JacksonKyle, OrcigaMichael-Angelo, SlavinMargaret

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study investigates the effects of ginger, grape pomace, and S-petasin (a constituent of butterbur extract) on CGRP secretion and calcium uptake, two mechanisms relevant to migraine. The findings suggest that these substances may have anti-inflammatory potential by preventing CGRP release, potentially through different mechanisms.
Paper Details　
Original Abstract of the Article :
Calcitonin gene-related peptide (CGRP) is a pivotal messenger in the inflammatory process in migraine. Limited evidence indicates that diet impacts circulating levels of CGRP, suggesting that certain elements in the diet may influence migraine outcomes. Interruption of calcium signaling, a mechanism...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963882/

データ提供：米国国立医学図書館（NLM）

Food Components and Migraine: A Culinary Journey Through CGRP

Migraine is like a sudden, intense sandstorm, disrupting the body's peaceful state. This study explores the fascinating connection between food components and the release of calcitonin gene-related peptide (CGRP), a key player in migraine inflammation. It's like a team of culinary detectives investigating the ingredients that might trigger or alleviate these debilitating headaches.

Dietary Influence on CGRP Secretion: A Potential Mechanism for Migraine

The researchers examine the effects of various food components on CGRP secretion, shedding light on a potential mechanism behind the dietary influence on migraine. They find that certain foods, like ginger and grape pomace, can significantly reduce CGRP release, offering a glimpse into potential dietary interventions for migraine prevention.

Food and Migraine: A Balancing Act

This study highlights the potential impact of dietary choices on migraine headaches. Understanding the complex interplay between food and CGRP release could lead to personalized dietary recommendations and potentially alleviate migraine symptoms.

Dr. Camel's Conclusion

Just as a camel's journey is influenced by the changing landscape, migraine experiences can be influenced by dietary choices. This research opens a new window into the intricate relationship between food and migraine, offering potential avenues for dietary intervention and better management of these debilitating headaches.
Date :
  1. Date Completed 2017-03-09
  2. Date Revised 2023-12-13
Further Info :

Pubmed ID

27376323

DOI: Digital Object Identifier

PMC4963882

Related Literature

Article Analysis
・Effective treatment of butterbur
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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