Long-term double-blinded unilateral pedunculopontine area stimulation in Parkinson's disease.

Author: HamaniClement, LangAnthony E, LozanoAndres M, MestreTiago A, MoroElena, PoonYu-Yan, SidiropoulosChristos

Paper Details 
Original Abstract of the Article :
BACKGROUND: Gait-related symptoms are often refractory to current available treatment options with a significant reduction in quality of life in Parkinson's disease. OBJECTIVES: The objective of this study was to determine the long-term efficacy and safety of unilateral pedunculopontine area stimul...See full text at original site
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引用元:
https://doi.org/10.1002/mds.26710

データ提供:米国国立医学図書館(NLM)

Pedunculopontine Area Stimulation: A New Oasis in the Desert of Parkinson's Disease

Parkinson's disease, a debilitating neurological disorder, often presents a challenging landscape for treatment. This study explores the potential of pedunculopontine area stimulation (PPS) as a new oasis for managing gait and balance impairments in Parkinson's disease, focusing on its long-term efficacy and safety. The authors conducted a double-blinded study to assess the impact of PPS on gait-related symptoms over a period of four years.

PPS: A Potential Oasis for Gait and Balance Challenges

The study revealed that PPS provided an initial but not sustained benefit for gait-related symptoms in Parkinson's disease. While patients experienced improvements in freezing of gait and falls at two years, these effects did not persist beyond four years. This suggests that PPS may provide temporary relief for gait-related challenges but its long-term effectiveness remains uncertain.

Navigating the Desert of Parkinson's Disease: Seeking Effective Therapies

The desert of Parkinson's disease can be a challenging journey, with its various symptoms and complications. This study explores a new oasis in the form of PPS, offering potential relief for gait and balance impairments. However, the long-term effectiveness of this treatment approach remains uncertain. It's crucial to continue exploring new avenues for managing Parkinson's disease and developing therapies that provide sustained relief for patients.

Dr.Camel's Conclusion

The desert of Parkinson's disease is a vast and complex landscape, and finding effective treatment options can be like searching for an oasis in a sandstorm. This study explores the potential of PPS as a new oasis for managing gait and balance challenges. While PPS offered an initial, but not sustained, benefit, further research is necessary to determine its long-term efficacy and explore alternative approaches for managing this debilitating disorder. The quest for effective therapies for Parkinson's disease continues, and we must continue to seek new oases in this arid landscape.

Date :
  1. Date Completed 2017-12-27
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

27392513

DOI: Digital Object Identifier

10.1002/mds.26710

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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