Premedication prevents infusion reactions and improves retention rate during infliximab treatment.

Author: BartoliFrancesca, BlagojevicJelena, BruniCosimo, CometiLaura, FioriGinevra, FurstDaniel E, GalluccioFelice, Matucci CerinicMarco, TofaniLorenzo

Paper Details 
Original Abstract of the Article :
Infliximab (IFX) is an anti-tumor necrosis factor-alpha antibody used to treat inflammatory joint diseases. Infusion reactions (IR) can occur during and after intravenous administration and often require discontinuation of IFX therapy. This retrospective study aimed at evaluating the incidence of IR...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/s10067-016-3351-5

データ提供:米国国立医学図書館(NLM)

Premedication Prevents Infusion Reactions

This study examines the effectiveness of premedication in preventing infusion reactions (IR) during treatment with infliximab, a medication used to treat inflammatory joint diseases. Imagine a camel carrying heavy loads across a vast desert. The camel needs proper preparation to endure the journey, just as patients receiving infliximab need premedication to minimize the risk of IR.

Premedication Reduces Infusion Reactions

The study compared three groups of patients receiving infliximab: one group received no premedication, another received a standard premedication protocol, and the third group received a more comprehensive premedication protocol. The results showed that premedication significantly reduced the incidence of IR, especially the more comprehensive protocol. This demonstrates that premedication is crucial for a smoother and safer infliximab treatment journey, like a camel carrying a well-packed load, making it easier to navigate the desert.

Benefits of Premedication for Patients

This study underscores the importance of premedication in infliximab treatment to minimize the occurrence of IR. Premedication can make the treatment journey more comfortable and less stressful for patients. It's like providing a camel with a sturdy saddle and protective gear to ensure a safe and comfortable journey. The findings contribute to improved patient care by enhancing safety and minimizing potential complications.

Dr. Camel's Conclusion

This research highlights the significance of premedication in infliximab treatment to reduce the risk of IR. It's a reminder that proper preparation is essential for a successful journey, just like a camel preparing for a long desert trek. The study emphasizes the importance of personalized treatment approaches and the potential for improving patient outcomes through careful premedication.
Date :
  1. Date Completed 2017-02-20
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

27436188

DOI: Digital Object Identifier

10.1007/s10067-016-3351-5

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.