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Effects of multiwalled carbon nanotubes on the bioavailability and toxicity of diphenhydramine to Pimephales promelas in sediment exposures.

Author: BlackMarsha C, HendersonW Matthew, MyerMark H

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study examined the combined effects of multiwalled carbon nanotubes (MWCNTs) and diphenhydramine (DPH) on juvenile fathead minnows. Addition of MWCNTs did not have a protective effect on DPH-related growth inhibition and did not reduce the whole-body burden of DPH in exposed fish.
Paper Details　
Original Abstract of the Article :
Multiwalled carbon nanotubes (MWCNTs) and pharmaceutical compounds are classified by the US Environmental Protection Agency as contaminants of emerging concern, with significant research devoted to determining their potential environmental and toxicological effects. Multiwalled carbon nanotubes are ...See full text at original site
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引用元：
https://doi.org/10.1002/etc.3561

データ提供：米国国立医学図書館（NLM）

Multiwalled Carbon Nanotubes and Diphenhydramine: A Complex Interaction in Aquatic Environments

Multiwalled carbon nanotubes (MWCNTs) and pharmaceutical compounds are emerging contaminants of concern, potentially posing risks to aquatic ecosystems. This research investigates the effects of MWCNTs on the bioavailability and toxicity of diphenhydramine (DPH), a common antihistamine, to fathead minnows (Pimephales promelas) in sediment exposures. The authors examine the potential for MWCNTs to alter DPH's bioavailability and toxicity, shedding light on the complex interactions of these contaminants in aquatic environments.

A Twisty Path: The Impact of MWCNTs on DPH

The study found that MWCNTs did not protect against DPH-related growth inhibition and did not reduce the whole-body burden of DPH in exposed fish. However, DPH adsorption to MWCNTs significantly reduced DPH concentrations in water and sediment. The study also revealed that P. promelas accumulates DPH adsorbed to MWCNTs in sediment through co-ingestion, highlighting the complex interplay of these contaminants in aquatic ecosystems.

Navigating the Waters: Understanding Contaminant Interactions

This research underscores the complex interactions between MWCNTs and pharmaceutical compounds in aquatic environments. While MWCNTs have potential applications in water remediation, the study highlights the need for careful consideration of their potential impacts on the bioavailability and toxicity of other contaminants.

Dr. Camel's Conclusion

Imagine a desert oasis teeming with life, but the water is contaminated. Just like a camel carefully choosing its water source, we must understand the complex interactions between contaminants in the environment. This research highlights the potential impact of MWCNTs on the bioavailability and toxicity of DPH in aquatic ecosystems, emphasizing the need for further research to ensure the safety of our waterways.

Date :
  1. Date Completed 2017-07-24
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

27442616

DOI: Digital Object Identifier

10.1002/etc.3561

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・Effects of diphenhydramine
SNS
PICO Info
in preparation
Languages

English

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