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Fertility-sparing surgery in epithelial ovarian cancer: a systematic review of oncological issues.

Author: BentivegnaE, ColomboN, GouyS, LearyA, MaulardA, MoriceP, PautierP

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review examined the feasibility and safety of fertility-sparing surgery (FSS) for early-stage epithelial ovarian cancer (EOC). The study explored the potential of FSS as a treatment option for preserving fertility in women with EOC, but highlights the need for careful patient selection and further research to confirm safety in certain subgroups.
Paper Details　
Original Abstract of the Article :
Since the last two decades, the feasibility of fertility-sparing surgery (FSS) in early-stage epithelial ovarian cancer (EOC) has been explored by several teams and is reconsidered in this systematic review undertaken using the PRISMA guidelines. Borderline ovarian tumours and non-EOCs were excluded...See full text at original site
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引用元：
https://doi.org/10.1093/annonc/mdw311

データ提供：米国国立医学図書館（NLM）

Fertility-Sparing Surgery for Epithelial Ovarian Cancer: A Balancing Act Between Oncological Safety and Fertility Preservation

This systematic review explores the feasibility and oncological safety of fertility-sparing surgery (FSS) in early-stage epithelial ovarian cancer (EOC). The review, based on data from 1150 patients and 139 relapsing patients reported by 21 teams, suggests that FSS can be safely considered for stage IA and IC grade 1 and 2 disease, and stage IC1 according to the new FIGO staging system. However, the safety of FSS for grade 2 disease remains unclear due to limited data. The review also indicates that FSS may be considered for stage I clear-cell tumors but should remain contraindicated for stage II/III disease. The study emphasizes the importance of careful patient selection, complete surgical staging, and expert pathological analysis to ensure optimal outcomes and balance oncological safety with fertility preservation.

Fertility-Sparing Surgery: A Viable Option for Selected Patients

The study’s findings suggest that FSS can be a viable option for carefully selected patients with early-stage epithelial ovarian cancer. This is a significant advancement, as it offers a potentially less invasive treatment option that preserves fertility for women facing a cancer diagnosis.

Navigating Cancer Treatment: A Personalized Approach

Cancer treatment is a complex and highly personalized journey. This study highlights the importance of considering individual factors, including disease stage, grade, and histologic subtype, when selecting treatment options. It’s like a camel navigating a complex desert ecosystem, choosing the right path depends on understanding the unique characteristics of the terrain. The study emphasizes the importance of personalized medicine and tailoring treatment plans to individual needs for optimal outcomes.

Dr. Camel's Conclusion

Just as a camel navigates a complex desert ecosystem, navigating cancer treatment requires careful consideration of individual factors. This systematic review provides valuable insights into the feasibility and safety of fertility-sparing surgery, emphasizing the need for a personalized approach to ensure optimal outcomes and balance oncological safety with fertility preservation.

Date :
  1. Date Completed 2017-12-26
  2. Date Revised 2020-02-06
Further Info :

Pubmed ID

27502723

DOI: Digital Object Identifier

10.1093/annonc/mdw311

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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