Acute effects of two dosages of orally administered midazolam on psychomotor performance in healthy volunteers.

Author: KlausnitzerW, SchafflerK

Paper Details 
Original Abstract of the Article :
The acute effects of two doses of orally administered midazolam (Dormicum, 10 and 30 mg) which as a putative anaesthetic premedicant is clinically expected to provide valid effects already after acute dosing on sedation parameters, were evaluated vs placebo within a randomized double-blind 3-period ...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/2757665

データ提供:米国国立医学図書館(NLM)

Midazolam's Effects on Psychomotor Performance: A Dose-Dependent Sedation

The human brain, a complex and intricate organ, is influenced by various factors, including medications. Midazolam, a commonly used sedative medication, is often administered before medical procedures to induce relaxation and reduce anxiety. This study investigated the acute effects of two doses of orally administered midazolam on psychomotor performance in healthy volunteers. The researchers aimed to determine the dose-dependent effects of midazolam on sedation levels and identify potential side effects.

A Dose-Dependent Journey: Midazolam's Influence on Performance

The study, like a caravan traversing the desert, revealed a dose-dependent increase in sedation with midazolam. This finding suggests that higher doses of midazolam lead to greater sedation. The study also noted subjective side effects associated with sedation, including mild and marked impairment of vigilance, depending on the dose. The findings highlight the importance of careful dose adjustments and monitoring of individual responses to midazolam.

Navigating the Desert of Consciousness: Midazolam's Impact on Psychomotor Function

Midazolam's effects on psychomotor performance are significant, particularly at higher doses. This research underscores the importance of caution when using midazolam, especially in situations where mental alertness and coordination are crucial. The study's findings provide valuable insights into the potential impact of midazolam on cognitive function and the need for careful consideration in prescribing and administering this medication. Like a camel navigating a sandstorm, individuals taking midazolam should be aware of the potential for altered mental states and take necessary precautions.

Dr.Camel's Conclusion

This study, like a star guiding travelers through the desert, provides valuable insights into the impact of midazolam on psychomotor performance. The dose-dependent sedation effects and potential side effects highlight the importance of careful dose selection and monitoring. This research underscores the complexity of the human brain and the need for cautious consideration when using medications that influence mental states.

Date :
  1. Date Completed 1989-09-01
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2757665

DOI: Digital Object Identifier

2757665

SNS
PICO Info
in preparation
Languages

English

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