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Managing adverse events associated with vismodegib in the treatment of basal cell carcinoma.

Author: FifeKate, HerdRobert, JonesSarah, LalondrelleSusan, LearJohn T, PlummerRuth, StrongAmy

Consensus Development ConferenceA conference organized by the National Institutes of Health (NIH) to develop consensus and recommendations on medical issues.
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ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Vismodegib is a hedgehog pathway inhibitor that is effective for treating advanced basal cell carcinomas. Common side effects of vismodegib are taste disturbances, muscle cramps and alopecia. Managing patient expectations, treatment breaks and quinine to alleviate muscle cramps, food swaps and dietician referral for taste disturbances were considered important for successfully managing side effects and allowing optimal treatment duration.
Paper Details　
Original Abstract of the Article :
Basal cell carcinomas are the most common form of skin cancer. Some develop into advanced cases not suitable for standard therapy. Vismodegib is the first-in-class oral hedgehog pathway inhibitor (which is dysregulated in 90% of basal cell carcinomas), and has demonstrated efficacy for advanced dise...See full text at original site
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引用元：
https://doi.org/10.2217/fon-2016-0296

データ提供：米国国立医学図書館（NLM）

Managing Adverse Events Associated With Vismodegib in the Treatment of Basal Cell Carcinoma

This study explores the use of vismodegib, a novel hedgehog pathway inhibitor, for treating advanced basal cell carcinomas. The authors delve into the management strategies for adverse events associated with vismodegib, including taste disturbances, muscle cramps, and alopecia. The study highlights the importance of managing patient expectations, implementing treatment breaks, and utilizing specific therapies like quinine to alleviate muscle cramps.

Navigating the Side Effects of Vismodegib

This study emphasizes the importance of proactively managing adverse events associated with vismodegib, a drug used to treat advanced basal cell carcinoma. It's like navigating a desert with potential dangers: being prepared to address these challenges can ensure a smoother and more successful journey. This research provides valuable insights into managing these side effects, allowing for more effective and comfortable treatment for patients.

Managing Basal Cell Carcinoma: A Multifaceted Approach

This study underscores the importance of a multi-faceted approach to managing basal cell carcinoma. It highlights the effectiveness of vismodegib but also acknowledges the need for managing potential side effects. It's like preparing for a desert expedition: having the right supplies and a plan to address potential obstacles can make all the difference. This research provides valuable insights into the intricacies of managing advanced basal cell carcinoma, reminding us that a well-rounded approach is crucial for optimizing patient care.

Dr.Camel's Conclusion

This study provides valuable insights into the management of adverse events associated with vismodegib, a promising drug for treating advanced basal cell carcinomas. It emphasizes the importance of addressing these side effects proactively and implementing strategies to mitigate their impact on patient well-being. This research underscores the importance of a comprehensive approach to treating cancer, acknowledging both the benefits and potential challenges of innovative therapies.

Date :
  1. Date Completed 2017-02-23
  2. Date Revised 2017-02-23
Further Info :

Pubmed ID

27640448

DOI: Digital Object Identifier

10.2217/fon-2016-0296

SNS
PICO Info
in preparation
Languages

English

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