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A randomised study for optimising crossover from ticagrelor to clopidogrel in patients with acute coronary syndrome. The CAPITAL OPTI-CROSS Study.
Author: , BernickJordan, ChongAun-Yeong, DickAlexander, FroeschlMichael, GloverChristopher, HibbertBenjamin, LabinazMarino, Le MayMichel R, LugomirskiPeter, MarquisJean-Francois, MazeRonnen, PourdjabbarAli, RamirezF Daniel, SimardTrevor, SoDerek Y F, WellsGeorge
Original Abstract of the Article :
Ticagrelor has been endorsed by guidelines as the P2Y<sub>12</sub> inhibitor of choice in patients with acute coronary syndrome. Clinically, some patients on ticagrelor will require a switch to clopidogrel; however, the optimal strategy and pharmacodynamics effects of switching remain unknown. Patie...See full text at original site
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引用元:
https://doi.org/10.1160/TH16-04-0340
データ提供:米国国立医学図書館(NLM)
Switching Antiplatelet Medications: A Balancing Act in Acute Coronary Syndrome
Acute coronary syndrome (ACS) is a serious heart condition that requires prompt and effective treatment. This study delves into the complex world of antiplatelet therapy for ACS patients, specifically focusing on the transition from ticagrelor to clopidogrel. The researchers investigated the optimal strategy for switching between these medications, considering the need for effective platelet inhibition while minimizing the risk of bleeding. The findings provide valuable insights for clinicians treating ACS patients, highlighting the importance of individualizing treatment decisions based on patient-specific factors.
Navigating the Antiplatelet Desert: Finding the Right Path
This study explores the delicate balance between effective platelet inhibition and minimizing bleeding risk in ACS patients. The researchers found that switching from ticagrelor to clopidogrel requires careful consideration, as the optimal strategy is not always straightforward. The study suggests that a bolus of clopidogrel may be beneficial in some cases, but more research is needed to determine its clinical significance. This highlights the importance of a personalized approach to antiplatelet therapy, taking into account the individual needs and risk profiles of each patient.
Antiplatelet Therapy and ACS: A Carefully Planned Journey
Treating acute coronary syndrome is like navigating a treacherous desert, where every step needs to be carefully planned. This study underscores the importance of personalized antiplatelet therapy, taking into account the specific needs and risks of each patient. The researchers' findings provide valuable insights for clinicians, highlighting the importance of continuous monitoring and adjustments to ensure optimal treatment outcomes.
Dr. Camel's Conclusion
The journey to effective antiplatelet therapy in ACS patients is like traversing a vast, unforgiving desert. This study highlights the importance of finding the right path, taking into account the individual needs and risks of each patient. It's a journey that requires careful planning, continuous monitoring, and a deep understanding of the complex interplay between medications and the human body. By working together, clinicians and patients can navigate this challenging terrain and find a path to optimal outcomes.
Date :
- Date Completed 2018-02-26
- Date Revised 2018-12-03
Further Info :
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