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Effects of clobazam for treatment of refractory status epilepticus.
Author: GernerStefan T, GeyerAnna, GollwitzerStephanie, HamerHajo M, HuttnerHagen B, KnappeRuben U, KuramatsuJoji B, MadžarDominik
Original Abstract of the Article :
BACKGROUND: Clobazam (CLB) is a well characterized antiepileptic drug (AED) that differs from other benzodiazepines by its basic chemical structure and pharmacodynamic properties. Only one previous study examined the efficacy of CLB as add-on therapy in refractory status epilepticus (RSE). METHODS:...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073816/
データ提供：米国国立医学図書館（NLM）
Clobazam: A Potential Treatment for Refractory Status Epilepticus
Status epilepticus (SE), a [serious neurological condition], can be challenging to treat. This research explores the efficacy of [clobazam (CLB)], an [antiepileptic drug (AED)], as an add-on therapy for [refractory status epilepticus (RSE)]. The study analyzes [70 RSE episodes], assessing the effectiveness of CLB in [terminating RSE]. The study found that [CLB was part of the AED regimen in 24/70 (34.3%) RSE episodes]. The study also found that [CLB was administered in clinically more complex RSE with longer RSE duration and worse outcome]. While CLB was not independently related to outcome, the study suggests that it might be a [reasonable AED and promising add-on agent] for treating RSE.
Clobazam: A Potential Tool for Managing Refractory Status Epilepticus
The study suggests that [clobazam might be a valuable tool] for managing refractory status epilepticus. The findings highlight the need for further research to fully explore its efficacy and determine its optimal application in this challenging condition. However, the study also emphasizes the importance of considering the complexity of each patient's situation and tailoring the treatment approach accordingly.
Navigating the Challenges of Status Epilepticus
Status epilepticus is a serious neurological condition that requires immediate medical attention. This research highlights the potential of clobazam as a treatment option for this challenging condition. Remember, just as a traveler in a desert might encounter unexpected challenges, managing status epilepticus often requires a multi-faceted approach, considering the individual needs of each patient.
Dr.Camel's Conclusion
The study suggests that clobazam could be a promising addition to the treatment regimen for refractory status epilepticus. However, further research is needed to fully explore its efficacy and determine its optimal application. Remember, just as a traveler in a desert must be prepared for unforeseen circumstances, managing status epilepticus often requires a flexible and adaptable approach.
Date :
- Date Completed 2017-01-02
- Date Revised 2019-12-10
Further Info :
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