Dual Therapy for Refractory Overactive Bladder in Children: A Prospective Open-Label Study.

Author: BlaisAnne-Sophie, BolducStéphane, GenoisLucie, MooreKatherine, MorinFannie, NadeauGeneviève

Paper Details 
Original Abstract of the Article :
Mirabegron (β3 adrenoreceptor agonist) is a new molecule with a mechanism of action distinct from antimuscarinics. Combination therapy with solifenacin was recently studied in an adult population. We evaluated the efficacy and safety of mirabegron as add-on therapy to treat urinary incontinence in c...See full text at original site
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引用元:
https://doi.org/10.1016/j.juro.2016.11.101

データ提供:米国国立医学図書館(NLM)

Dual Therapy for Refractory Overactive Bladder in Children: Expanding the Oasis of Treatment Options

Overactive bladder (OAB) is a common condition, often described as a desert of urinary urgency and incontinence. This condition can be particularly challenging for children, as it can impact their quality of life and social interactions. This study investigates the effectiveness of mirabegron as add-on therapy for children with OAB who are refractory or intolerant to antimuscarinic medications.

The researchers found that mirabegron, in combination with solifenacin, showed promising results in improving urinary incontinence in children with OAB. This is like finding a new and effective source of water in the desert, offering a potential solution for those who haven't found relief from traditional treatments. The findings suggest that mirabegron could be a valuable addition to the treatment arsenal for children with OAB.

Expanding the Oasis of Treatment Options

This research explores a new and promising approach for treating OAB in children. The findings offer hope for children who haven't found relief with traditional therapies. It's a step toward creating a more diverse and effective oasis of treatment options, providing greater comfort and control for children struggling with OAB. This could help them navigate the desert of bladder issues with more confidence and ease.

Navigating the Desert of Bladder Issues

Overactive bladder can be a challenging condition for children, but this research offers a glimmer of hope. The findings highlight the importance of exploring different treatment options and tailoring therapies to meet the specific needs of each child. It's a reminder that even in the seemingly vast and barren desert of bladder issues, there are oases of hope and effective treatment options waiting to be discovered.

Dr.Camel's Conclusion

This research explores a new and promising approach to treating overactive bladder in children, offering a potential oasis in the desert of urinary issues. The findings highlight the importance of seeking diverse treatment options to address this challenging condition, providing greater comfort and control for children struggling with OAB.

Date :
  1. Date Completed 2019-03-11
  2. Date Revised 2019-03-11
Further Info :

Pubmed ID

27914999

DOI: Digital Object Identifier

10.1016/j.juro.2016.11.101

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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