Paper Details 
Original Abstract of the Article :
PURPOSE: The physical compatibility of isavuconazonium sulfate with 95 i.v. drugs during simulated Y-site administration was studied. METHODS: Isavuconazonium sulfate for injection and all other drugs were reconstituted according to the manufacturer's recommendation and further diluted with 0.9% so...See full text at original site
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引用元:
https://doi.org/10.2146/ajhp150733

データ提供:米国国立医学図書館(NLM)

Isavuconazonium Sulfate Compatibility: A Crucial Consideration for IV Drug Administration

Isavuconazonium sulfate is an antifungal medication used to treat serious fungal infections. This research explores the physical compatibility of isavuconazonium sulfate with other commonly used IV drugs. Researchers simulated Y-site administration, a common practice in which multiple medications are mixed and administered together, to determine which drugs can be safely combined with isavuconazonium sulfate.

Navigating Drug Interactions: Ensuring Safety and Effectiveness

The study found that isavuconazonium sulfate was physically compatible with a significant number of IV drugs when administered in 0.9% sodium chloride injection or 5% dextrose injection. However, incompatibility was observed with a number of antimicrobials, including cephalosporins, and other IV medications. This research is like a desert guide, helping us navigate the complex terrain of drug interactions to ensure safe and effective medication administration.

Understanding Drug Compatibility: A Key to Safe Medication Administration

This research underscores the importance of understanding drug compatibility, particularly when administering medications intravenously. Consulting with a pharmacist or healthcare professional is essential to determine the safe and effective combinations of medications for individual patients. Think of this research as a reminder that careful planning and collaboration are crucial in ensuring the safe and effective delivery of IV medications, just as a desert traveler relies on a trusted guide to navigate the challenging terrain.

Dr.Camel's Conclusion

This research provides valuable information regarding the physical compatibility of isavuconazonium sulfate with other IV medications. The study's findings underscore the importance of considering drug compatibility to ensure safe and effective administration, particularly when administering medications intravenously. This research, like a well-marked trail in the desert, provides a guide for navigating the complex landscape of drug interactions and ensuring the safety and well-being of patients.

Date :
  1. Date Completed 2018-07-17
  2. Date Revised 2019-01-01
Further Info :

Pubmed ID

28007722

DOI: Digital Object Identifier

10.2146/ajhp150733

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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