Paper Details
- Home
- Paper Details
Genetic variants associated with angiotensin-converting enzyme inhibitor-induced cough: a genome-wide association study in a Swedish population.
Author: AxelssonTomas, CavalliMarco, ErikssonNiclas, HallbergPär, JohanssonHans-Erik, MagnussonPatrik Ke, NorlingPia, PerssonMatilda, WadeliusClaes, WadeliusMia, YueQun-Ying
Original Abstract of the Article :
AIM: We conducted a genome-wide association study on angiotensin-converting enzyme inhibitor-induced cough and used our dataset to replicate candidate genes identified in previous studies. PATIENTS & METHODS: A total of 124 patients and 1345 treated controls were genotyped using Illumina arrays. Th...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.2217/pgs-2016-0184
データ提供:米国国立医学図書館(NLM)
Exploring Genetic Factors Associated with Angiotensin-Converting Enzyme Inhibitor-Induced Cough
Angiotensin-converting enzyme inhibitors (ACEIs) are widely prescribed medications for managing hypertension, but they can sometimes cause a persistent cough as a side effect. This study investigates potential genetic factors associated with ACEI-induced cough, seeking to identify genes that may contribute to this adverse reaction. The researchers conducted a genome-wide association study (GWAS) on a Swedish population, comparing the genetic profiles of individuals who experienced ACEI-induced cough with those who did not. The study aimed to identify potential genetic markers that could predict susceptibility to ACEI-induced cough. The study identified several genes that were potentially associated with ACEI-induced cough, suggesting that genetic factors may play a role in determining an individual's susceptibility to this side effect.
Genetic Insights into ACEI-Induced Cough
The study's findings provide intriguing insights into the potential genetic basis for ACEI-induced cough, suggesting that genetic predisposition may contribute to this side effect.
Health Implications and Practical Applications
Imagine a desert oasis, where the delicate balance of its ecosystem can be disrupted by a single factor. Similarly, the individual response to medications can be influenced by a complex interplay of genetic and environmental factors. This study highlights the importance of considering genetic factors in personalized medicine, allowing healthcare providers to better tailor treatment strategies to individual patients.
Dr.Camel's Conclusion
This study provides valuable insights into the potential genetic factors contributing to ACEI-induced cough. By identifying these genes, the research opens up new avenues for understanding and potentially predicting this side effect, paving the way for more personalized and effective treatment strategies.
Date :
- Date Completed 2017-07-24
- Date Revised 2017-07-24
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.