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In vitro activity of the antiasthmatic drug zafirlukast against the oral pathogens Porphyromonas gingivalis and Streptococcus mutans.
Author: BeullensSerge, CammueBruno P A, De BruckerKatrijn, De CremerKaat, FauvartMaarten, GeritsEvelien, MichielsJan, ThevissenKarin, Van der MassenIsolde, VandammeKatleen, VerstraetenNatalie
Original Abstract of the Article :
Oral infections are among the most common diseases worldwide. Many protocols for the prevention and treatment of oral infections have been described, yet no golden standard has been developed so far. The antiseptic chlorhexidine and antibiotics are often used in these treatment procedures. However, ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1093/femsle/fnx005
データ提供:米国国立医学図書館(NLM)
Zafirlukast: An Antiasthmatic Drug with Antibacterial Potential
Oral infections are a common concern for many individuals. This research explores the potential of zafirlukast, an antiasthmatic drug, to combat oral pathogens, opening up new avenues for treating oral infections. The researchers investigated the antibacterial activity of zafirlukast against two common oral pathogens, *Porphyromonas gingivalis* and *Streptococcus mutans*, and demonstrated its effectiveness against biofilms. The study suggests that zafirlukast might offer a novel therapeutic approach to treating oral infections.
Beyond Asthma Treatment: Zafirlukast's Antibacterial Potential
The researchers discovered that zafirlukast exhibited antibacterial activity against two common oral pathogens. This finding suggests that zafirlukast, beyond its role in asthma treatment, could potentially be used to combat oral infections. It's like finding a hidden oasis in the desert, a new resource that can be used for different purposes.
A New Frontier in Oral Health
This study opens up a new frontier in oral health research by suggesting that zafirlukast could be used to treat oral infections. The findings encourage further investigation into the potential of this antiasthmatic drug to combat oral pathogens, offering a promising new avenue for addressing a prevalent health concern. Just as a desert traveler explores new paths to find resources, so too must we continue to explore the potential of existing medications in novel ways.
Dr.Camel's Conclusion
This research delves into the fascinating world of drug repurposing, suggesting that zafirlukast, an antiasthmatic drug, could potentially be used to combat oral infections. The findings encourage further research to explore the full potential of this medication in treating oral health issues. Just as a camel adapts to the ever-changing desert environment, so too must we adapt our approach to medical treatments to embrace new possibilities and improve the lives of our patients.
Date :
- Date Completed 2017-05-08
- Date Revised 2021-12-04
Further Info :
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