Effectiveness and Safety of Sitagliptin in Patients with Beta-thalassaemia Major and Diabetes Mellitus: A Case Series.

Author: BarnardMaria, JonesRomilla, PrescottEmma, ShahFarrukh T, TzoulisPloutarchos, ZonooziShahrzad

Paper Details 
Original Abstract of the Article :
Sitagliptin, a modern antidiabetic agent which is weight neutral and associated with low rate of hypoglycaemias, is being increasingly used in type 2 diabetes mellitus (DM). However, there is a paucity of data about its efficacy and safety in beta-thalassaemia major (β-TM). This retrospective case s...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224814/

データ提供:米国国立医学図書館(NLM)

Sitagliptin: A New Oasis for Managing Diabetes in Beta-Thalassemia Major

Beta-thalassemia major (β-TM) is a genetic blood disorder that can lead to complications such as diabetes. This study investigates the effectiveness and safety of sitagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, in managing diabetes in patients with β-TM. The researchers evaluated the impact of sitagliptin on glycemic control, hypoglycemia, and overall well-being in a small group of patients with β-TM and diabetes.

Sitagliptin: A Potential Oasis for Diabetes Management in β-TM

The researchers found that sitagliptin was effective in improving glycemic control and reducing the frequency of hypoglycemia in most patients with β-TM and diabetes. This suggests that sitagliptin may offer a valuable tool for managing diabetes in this challenging population, providing a potential oasis of relief in the desert of β-TM-associated diabetes.

Navigating the Desert of β-TM and Diabetes: Finding the Right Path

This study provides encouraging evidence for the potential benefits of sitagliptin in managing diabetes in patients with β-TM. It's important to note that the study involved a small sample size, and further research is needed to confirm these findings. As we navigate the complex and challenging landscape of β-TM and diabetes, it's essential to explore new therapeutic options and personalize treatment plans based on individual patient needs.

Dr.Camel's Conclusion

This study offers promising insights into the potential use of sitagliptin for managing diabetes in patients with β-TM. It's a reminder that ongoing research and exploration of new treatment options are crucial for improving the lives of individuals with this complex blood disorder. We continue to seek new oases in the desert of β-TM research, striving to provide effective and safe treatment options for those affected by this genetic condition.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-10-01
Further Info :

Pubmed ID

28101310

DOI: Digital Object Identifier

PMC5224814

Related Literature

SNS
PICO Info
in preparation
Languages

English

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