Paper Details

  1. Home
  2. Paper Details

Effect and safety of paroxetine combined with zolpidem in treatment of primary insomnia.

Author: LiuY, MaoH J, SongM F, TangG Z, WangS D, XuX H, YinY, YuZ H

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effectiveness of zolpidem combined with paroxetine in the treatment of primary insomnia. The study found that the combination treatment was more effective than zolpidem treatment alone in sleep maintenance and early morning awakenings.
Paper Details　
Original Abstract of the Article :
PURPOSE: Primary insomnia is a persistent and recurrent disorder as well as a risk factor for depression. The aim of this study was to determine whether the zolpidem combined with paroxetine would be effective in the treatment of patients with primary insomnia. METHODS: Ninety patients meeting DSM-...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s11325-017-1462-0

データ提供：米国国立医学図書館（NLM）

The Efficacy of Paroxetine and Zolpidem for Insomnia

The [treatment of primary insomnia] is like a long, arduous journey through a sleep-deprived desert. This study focuses on the potential benefits of combining [paroxetine] and [zolpidem] to alleviate the symptoms of this persistent and often debilitating sleep disorder. The researchers utilized a [randomized controlled trial] to compare the efficacy of the combination treatment to a control group receiving [zolpidem] alone. This study's findings offer a valuable glimpse into the potential of [combination therapy] for improving sleep quality and tackling the underlying causes of insomnia.

The Impact of Combination Therapy on Sleep Quality

The study demonstrated that [the combination of paroxetine and zolpidem] was significantly more effective than zolpidem alone in improving [sleep maintenance, early morning awakenings, and overall sleep quality]. These findings suggest that combining a [selective serotonin reuptake inhibitor (SSRI)] like paroxetine with a [benzodiazepine receptor agonist] like zolpidem may offer a synergistic approach to managing insomnia.

The Importance of Addressing Sleep Disorders

The study's findings highlight the importance of taking a comprehensive approach to treating sleep disorders, particularly [primary insomnia]. This may involve a combination of [pharmacotherapy, behavioral interventions, and lifestyle adjustments]. Addressing the root causes of insomnia and optimizing sleep hygiene are essential for restoring sleep quality and improving overall well-being.

Dr.Camel's Conclusion

As a seasoned researcher who has spent countless nights under the stars, I know firsthand the importance of a good night's sleep. This study provides valuable insights into the potential of [combination therapy] to effectively manage insomnia. The use of [paroxetine and zolpidem] holds promise for helping individuals navigate the challenging desert of sleepless nights.
Date :
  1. Date Completed 2018-02-26
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28101753

DOI: Digital Object Identifier

10.1007/s11325-017-1462-0

Related Literature

Article Analysis
・Effective treatment of insomnia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.