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Metformin during ovulation induction with gonadotrophins followed by timed intercourse or intrauterine insemination for subfertility associated with polycystic ovary syndrome.

Author: BordewijkEsmée M, CostelloMichael F, MolBen Willem J, NahuisMarleen, TsoLeopoldo O, Van der VeenFulco, van WelyMadelon

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Clomiphene citrate (CC) is the usual first treatment for women with ovulation problems due to PCOS. If CC doesn't work, follicle-stimulating hormone (FSH) is used. Metformin, a medication for diabetes, may improve the effectiveness of FSH and make treatment safer by reducing the risk of multiple pregnancies.
Paper Details　
Original Abstract of the Article :
Clomiphene citrate (CC) is generally considered first-line treatment in women with anovulation due to polycystic ovary syndrome (PCOS). Ovulation induction with follicle-stimulating hormone (FSH; gonadotrophins) is second-line treatment for women who do not ovulate or conceive while taking CC. Metfo...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464837/

データ提供：米国国立医学図書館（NLM）

Metformin: A Powerful Ally in the Desert of PCOS

Polycystic ovary syndrome (PCOS) is a hormonal disorder that can affect a woman's reproductive health. It's like a desert landscape, where the ovaries are overgrown with cysts and the hormones are out of balance, making it difficult to conceive. This study explored the potential of metformin, a drug commonly used for type 2 diabetes, to improve the effectiveness of ovulation induction with gonadotropins in women with PCOS. The researchers hypothesized that metformin could enhance ovulation and potentially reduce the risk of multiple pregnancies. It's like discovering a hidden spring in the desert, a source of fertility that can help women overcome the challenges of PCOS.

Metformin: A Refreshing Oasis in the Desert of PCOS

While further research is needed to confirm the findings, this study suggests that metformin could play a valuable role in ovulation induction for women with PCOS. It's like finding a refreshing oasis in the desert, a place where the ovaries can bloom and the hormones can return to a state of balance. This could significantly increase the chances of conception and reduce the risk of complications.

Navigating the Desert of PCOS: Finding the Right Path to Fertility

If you are struggling with PCOS and trying to conceive, it's important to talk to your doctor about your treatment options. Metformin could be a valuable tool in your journey to fertility. Remember, navigating the desert of PCOS requires a collaborative approach, working with your doctor to find the right path to achieve your reproductive goals.

Dr.Camel's Conclusion

This study provides a promising glimpse into the potential of metformin for improving ovulation induction in women with PCOS. It's a reminder that even in the face of challenging reproductive health conditions, we can continue to explore innovative treatments and seek solutions that offer hope for a brighter future. It's like discovering a new oasis in the vast desert of reproductive health, a place where fertility and dreams can blossom.

Date :
  1. Date Completed 2017-04-21
  2. Date Revised 2022-04-10
Further Info :

Pubmed ID

28118681

DOI: Digital Object Identifier

PMC6464837

Related Literature

Article Analysis
・Effective treatment of polycystic ovary syndrome
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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