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Fear conditioning and extinction in pediatric obsessive-compulsive disorder.

Author: BrittonJennifer C, GellerDaniel A, McGuireJoseph F, MurphyTanya K, OrrScott P, PineDaniel S, SmallBrent J, StorchEric A, WilhelmSabine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the differences in fear acquisition and extinction between youths with obsessive-compulsive disorder (OCD) and healthy controls. The study found that participants with OCD exhibited a stronger orienting SCR to initial stimuli, a larger SCR to the CS+, and a larger absolute magnitude of the unconditioned fear response. During extinction, OCD participants continued to exhibit a differential SCR to the CS+ and CS-, whereas HC participants exhibited diminished SCR to both stimuli.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Fear acquisition and extinction are central constructs in the cognitive-behavioral model of obsessive-compulsive disorder (OCD), which underlies exposure-based cognitive-behavioral therapy. Youths with OCD may have impairments in fear acquisition and extinction that carry treatment impli...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/28207912

データ提供：米国国立医学図書館（NLM）

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Date :
  1. Date Completed 2018-02-05
  2. Date Revised 2019-12-10
Further Info :

Pubmed ID

28207912

DOI: Digital Object Identifier

NIHMS967860

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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