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EFFICACY OF TACROLIMUS FOR INDUCTION OF REMISSION IN PATIENTS WITH MODERATE-TO-SEVERE ULCERATIVE COLITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS.

Author: LasaJuan, OliveraPablo

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study reviewed 22 studies on the use of tacrolimus, a calcineurin inhibitor, for inducing remission in patients with moderate-to-severe ulcerative colitis. The study found that tacrolimus was more effective than placebo at inducing remission, with a lower risk of treatment failure.
Paper Details　
Original Abstract of the Article :
BACKGROUND: There is evidence that shows that calcineurin inhibitors may be useful for the treatment of severe ulcerative colitis. However, evidence regarding the efficacy of tacrolimus for remission induction in this setting is scarce. OBJECTIVE: To develop a systematic review on the existing evid...See full text at original site
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引用元：
https://doi.org/10.1590/s0004-2803.201700000-15

データ提供：米国国立医学図書館（NLM）

Tacrolimus: A Potential Oasis in the Desert of Ulcerative Colitis

Ulcerative colitis, a chronic inflammatory bowel disease, can be a challenging condition to live with. It can feel like navigating a harsh and unforgiving desert, filled with discomfort and unpredictable symptoms. This research investigates the effectiveness of tacrolimus, a medication, in inducing remission in patients with moderate-to-severe ulcerative colitis. The study aims to find a new oasis in the desert, offering a potential treatment for individuals struggling with this debilitating condition. Researchers reviewed existing evidence on the efficacy of tacrolimus, finding promising results in reducing disease activity and achieving remission. This suggests that tacrolimus could provide a vital source of relief in the desert of ulcerative colitis.

Tacrolimus: A Beacon of Hope in the Desert of Ulcerative Colitis

The research indicates that tacrolimus shows promise as a therapeutic alternative for inducing remission in patients with moderate-to-severe ulcerative colitis. The study highlights the potential of tacrolimus to offer a new path to healing, providing a more comfortable and fulfilling life for individuals struggling with this chronic condition. It suggests that tacrolimus could play a significant role in improving outcomes and quality of life for those affected by ulcerative colitis.

Navigating the Desert of Ulcerative Colitis: A Journey of Hope and Healing

The study underscores the importance of exploring new and effective treatment options for ulcerative colitis. It highlights the potential of tacrolimus to provide a much-needed oasis in the desert of this condition, offering hope for symptom relief and improved quality of life. Individuals with ulcerative colitis should discuss potential treatment options with a healthcare provider to find the best path to healing and manage the challenging terrain of this chronic condition.

Dr. Camel's Conclusion

This research offers a glimmer of hope for individuals with ulcerative colitis. Tacrolimus holds potential as a valuable therapeutic option for inducing remission, providing a much-needed oasis in the desert of this condition. Remember, just as a desert traveler seeks out water sources, it's important to actively seek out and discuss treatment options with healthcare providers to navigate the challenging terrain of ulcerative colitis and find the path to healing.

Date :
  1. Date Completed 2017-06-29
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28327826

DOI: Digital Object Identifier

10.1590/s0004-2803.201700000-15

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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