Paper Details

  1. Home
  2. Paper Details

Decitabine treatment for acute myeloid leukemia relapse after allogeneic hematopoietic stem cell transplantation.

Author: GaoS J, LiuX L, TanY H, WangC, ZhaoX

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study presents a case report of a 49-year-old female with acute myeloid leukemia (AML) who experienced relapse after allogeneic stem cell transplantation. The patient achieved complete remission after one cycle of decitabine treatment, suggesting its potential as a suitable treatment option for AML relapse in this setting.
Paper Details　
Original Abstract of the Article :
Therapeutic options for patients with relapse of acute myeloid leukemia (AML) after allo-SCT are limited. Here, we present a case of a 49-year female with AML who underwent myeloablative allo-SCT from a matched sibling donor. Seven months after transplantation she developed cGVHD and suffered from e...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/28337888

データ提供：米国国立医学図書館（NLM）

Decitabine for Acute Myeloid Leukemia Relapse: A Case Report

This study presents a case report of a patient with [acute myeloid leukemia (AML)] who experienced relapse after undergoing [allogeneic hematopoietic stem cell transplantation]. The authors describe the patient's treatment with [decitabine] and discuss the potential effectiveness of this drug in this specific setting. Think of this case study as a single sand dune in the vast desert of cancer research, providing a unique perspective on a specific challenge.

Decitabine: A Potential Treatment Option for AML Relapse

The study provides evidence that decitabine may be a suitable treatment option for AML relapse after allogeneic transplantation. The authors report a case of a patient who achieved complete remission after receiving decitabine treatment. This finding offers hope for patients who experience AML relapse after transplantation. This discovery is like finding a rare and precious water source in the desert - it provides a lifeline for those in need.

Exploring the Use of Decitabine for AML Relapse

This case report encourages further research into the use of decitabine for AML relapse after allogeneic transplantation. The authors suggest that additional clinical trials are needed to fully assess the efficacy and safety of this drug in this specific patient population. This is like exploring a new path through the desert - we need to carefully evaluate its feasibility and potential benefits before making it a standard route.

Dr. Camel's Conclusion

This case report provides a promising example of the potential benefits of decitabine for treating AML relapse after allogeneic transplantation. The findings warrant further investigation to explore the full potential of this drug for improving patient outcomes. This research is like a single drop of water in the desert - it may seem small, but it can offer a glimmer of hope for a parched traveler.

Date :
  1. Date Completed 2017-06-01
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28337888

DOI: Digital Object Identifier

25

Related Literature

Article Analysis
・Side Effects of azacitidine
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.