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Impact of antiviral therapy on hepatocellular carcinoma and mortality in patients with chronic hepatitis C: systematic review and meta-analysis.

Author: BangChang Seok, SongIl Han

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study assessed the long-term clinical outcomes of antiviral therapy for chronic hepatitis C infection, examining the impact of treatment on the development of hepatocellular carcinoma (HCC) and mortality based on antiviral treatment response.
Paper Details　
Original Abstract of the Article :
The long-term clinical outcomes of antiviral therapy for patients with chronic hepatitis C are uncertain in terms of hepatitis C virus (HCV)-related morbidity and mortality according to the response to antiviral therapy. This study aimed to assess the impact of antiviral treatment on the development...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379714/

データ提供：米国国立医学図書館（NLM）

Impact of Antiviral Therapy on Hepatocellular Carcinoma and Mortality in Patients with Chronic Hepatitis C

This study delves into the critical field of hepatitis C treatment. It examines the long-term impact of antiviral therapy on patients with chronic hepatitis C, focusing on the development of hepatocellular carcinoma (HCC), a type of liver cancer, and overall mortality. The researchers aimed to assess the effectiveness of antiviral treatment in reducing the risk of HCC and improving survival rates in these patients.

The study utilized a systematic review and meta-analysis approach, combining the results of multiple previous studies to provide a comprehensive overview of the evidence. The researchers looked at the impact of antiviral treatment on the development of HCC and mortality in patients with chronic hepatitis C, taking into account the individual response to therapy. Their analysis revealed that antiviral therapy significantly reduced the risk of developing HCC and mortality in patients with chronic hepatitis C, highlighting the crucial role of early and effective treatment in managing this serious viral infection.

Antiviral Therapy and Improved Outcomes for Hepatitis C Patients

This research provides compelling evidence that antiviral therapy can significantly improve outcomes for patients with chronic hepatitis C. Early and effective treatment not only helps manage symptoms but also reduces the risk of developing serious complications, such as HCC and premature death.

Liver Health and Management of Hepatitis C

The study underscores the importance of early diagnosis and treatment for hepatitis C. Regular screening and prompt initiation of appropriate antiviral therapy can significantly reduce the long-term risks associated with this viral infection, improving the health and well-being of affected individuals.

Dr.Camel's Conclusion

This comprehensive analysis provides strong evidence that antiviral therapy is a crucial intervention for patients with chronic hepatitis C. The study reveals that effective treatment can significantly reduce the risk of developing liver cancer and improve overall survival rates. These findings emphasize the importance of early diagnosis and access to timely and effective treatment for patients with this debilitating viral infection.
Date :
  1. Date Completed 2017-10-24
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

28376711

DOI: Digital Object Identifier

PMC5379714

Related Literature

Article Analysis
・Effective treatment of hepatitis c
SNS
PICO Info
in preparation
Languages

English

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