Randomized, placebo-controlled study of cetirizine and loratadine in children with seasonal allergic rhinitis.

Author: BergerWilliam E, FranklinKathleen B, LaForceCraig F, NayakAnjuli S, PatelMitesh K, UrdanetaEduardo R, WuMei-Miau

Paper Details 
Original Abstract of the Article :
BACKGROUND: Pharmacologic treatment is a mainstay of allergy therapy and many caregivers use over-the-counter antihistamines for the treatment of seasonal allergic rhinitis (SAR) symptoms in children. OBJECTIVE: To assess the efficacy and safety of cetirizine 10 mg syrup versus loratadine 10 mg syr...See full text at original site
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引用元:
https://doi.org/10.2500/aap.2017.38.4050

データ提供:米国国立医学図書館(NLM)

Cetirizine vs. Loratadine: A Comparative Study for Seasonal Allergic Rhinitis

Seasonal allergic rhinitis (SAR), commonly known as hay fever, is a common ailment that affects millions, causing uncomfortable symptoms like sneezing, runny nose, and itchy eyes. Antihistamines, such as cetirizine and loratadine, are often used to alleviate these symptoms. This study explores the relative effectiveness of these two medications in children with SAR, a group particularly susceptible to allergies. The researchers conducted a randomized, double-blind, placebo-controlled trial, a robust research design that helps eliminate bias and ensure reliable results.

Cetirizine: A Potential Edge in Symptom Relief

The study found that cetirizine was significantly more effective than a placebo in reducing SAR symptoms in children aged 6-11 years. Both cetirizine and loratadine showed similar effectiveness, although the difference between them was not statistically significant. These findings suggest that cetirizine might offer slightly better symptom relief for children with SAR. However, it's important to note that loratadine is also a viable option and may be suitable for some children.

Navigating Allergy Management

This research provides valuable insights into the treatment of SAR in children. It's important to consult with a healthcare professional to determine the most appropriate treatment for your child, taking into account individual factors and potential side effects. Additionally, exploring other allergy management strategies, such as avoiding triggers, can contribute to overall symptom control.

Dr. Camel's Conclusion

This study underscores the importance of choosing the right medication for individual needs. While both cetirizine and loratadine can be effective for SAR, cetirizine appears to offer a slight advantage in reducing symptoms in children. Remember, a personalized approach to allergy management is key to finding the best solution for each individual.

Date :
  1. Date Completed 2018-02-12
  2. Date Revised 2018-02-12
Further Info :

Pubmed ID

28441993

DOI: Digital Object Identifier

10.2500/aap.2017.38.4050

Related Literature

SNS
PICO Info
in preparation
Languages

English

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