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Two-year antibody persistence in children vaccinated at 12-15 months with a measles-mumps-rubella virus vaccine without human serum albumin.

Author: Abu-ElyazeedRemon, BaccariniCarmen, BerryAndrea A, CarbayoAntonio, Diaz-PerezClemente, GroggStanley, HarrisonChristopher J, HenryOuzama, InnisBruce L, LeonardiMichael, MufsonMaurice A, PeltierChristopher, PoveyMichael, ShapiroSteven, TwiggsJerry D

Clinical Trial, Phase IIA Phase II trial is a trial that further evaluates the efficacy and safety of a new drug or treatment, whose safety has been confirmed to some extent in a Phase I trial, in a small number of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study investigated the persistence of antibodies against measles, mumps, and rubella in children who received one dose of either the M-M-R II or MMR-RIT vaccine at 12-15 months of age. Seropositivity for measles and rubella remained high at 2 years post-vaccination. Antibody persistence for mumps was also observed. Both vaccines were well-tolerated.
Paper Details　
Original Abstract of the Article :
One combined measles-mumps-rubella (MMR) vaccine without Human Serum Albumin (HSA) is currently licensed in the USA (M-M-R II; Merck, USA) and another has been developed (Priorix™ [MMR-RIT, GSK, Belgium]). In this follow-up study, children from USA or Puerto Rico, who had received one dose of M-M-R ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512763/

データ提供：米国国立医学図書館（NLM）

MMR Vaccines: A Safe and Effective Oasis in the Desert of Childhood Immunization

Measles, mumps, and rubella are highly contagious diseases that can have serious consequences, particularly for children. This study, published in [Journal Name], evaluates the long-term antibody persistence and safety of two measles-mumps-rubella (MMR) vaccines without human serum albumin (HSA) in children vaccinated at 12-15 months of age. The researchers followed up the children for two years after vaccination, measuring antibody levels and recording adverse events. The study found that both MMR vaccines provided high and sustained antibody levels for two years, with a favorable safety profile.

MMR Vaccines: A Beacon of Hope in the Desert of Childhood Infections

This study provides reassuring evidence for the long-term effectiveness and safety of MMR vaccines. It's like finding a beacon of hope in the vast desert of childhood infections, offering parents a safe and reliable way to protect their children from these potentially devastating diseases.

Childhood Immunization: A Vital Oasis in the Desert of Health

Vaccination is a cornerstone of public health, safeguarding children from preventable diseases. This study underscores the importance of adhering to recommended immunization schedules to protect our children and build a healthier future. Remember, vaccination is a vital oasis in the desert of health, providing a lifeline against infectious diseases and ensuring a brighter future for our children.

Dr. Camel's Conclusion

This study confirms the long-term effectiveness and safety of MMR vaccines without HSA. It's like discovering a reliable source of water in the desert of childhood immunization, offering parents a safe and effective way to protect their children from preventable diseases. Remember, vaccination is a powerful tool for safeguarding our children's health and building a healthier future. Let's continue to spread awareness and ensure that everyone has access to this vital oasis of protection.

Date :
  1. Date Completed 2018-03-14
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28481690

DOI: Digital Object Identifier

PMC5512763

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SNS
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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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