Iloprost Instillation in Two Neonates with Pulmonary Hypertension.

Author: AksuMeltem, AktasSelma, AtalayYildiz, HirfanogluIbrahim M, TurkyilmazCanan, UnalSezin

Paper Details 
Original Abstract of the Article :
Pulmonary hypertension may coexist with certain diseases in neonates. Iloprost inhalation is one of the treatments which cause selective pulmonary vasodilatation. Inhalation is not an easy way of drug administration in mechanically ventilated infants; as some exhibit desaturations during inhalation....See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/28492159

データ提供:米国国立医学図書館(NLM)

Iloprost: A Breath of Fresh Air for Pulmonary Hypertension

The field of [neonatal pulmonary hypertension] investigates the challenges of managing this serious condition in infants. This study explores the use of iloprost, a pulmonary vasodilator, in two neonates with pulmonary hypertension. The authors describe their clinical experience with iloprost instillation during mechanical ventilation, evaluating its effectiveness and safety in these vulnerable patients.

Iloprost Instillation: A New Route for Treatment

The study reveals that iloprost instillation was well-tolerated in the term infant with diaphragmatic hernia, but significant blood pressure fluctuations were observed in the preterm infant. These findings suggest that iloprost instillation may be a viable treatment option for term neonates with resistant pulmonary hypertension, but caution is warranted in preterm infants due to potential side effects. Further research is needed to optimize iloprost administration and understand its impact on different patient populations.

A Glimpse of Hope: Improving Neonatal Care

This study underscores the importance of individualized care in neonatal pulmonary hypertension, considering the unique challenges faced by preterm and term infants. The findings pave the way for exploring new treatment approaches and optimizing existing therapies to improve the outcomes for these vulnerable patients.

Dr.Camel's Conclusion

Like a camel traversing a desert landscape, newborn infants with pulmonary hypertension face significant challenges. This study explores the use of iloprost as a potential treatment option, highlighting the need for careful consideration and individualized care in managing this complex condition. As we continue to advance our understanding of neonatal pulmonary hypertension, we can work towards a future where all infants have the best possible chance at a healthy start.

Date :
  1. Date Completed 2018-01-16
  2. Date Revised 2018-01-16
Further Info :

Pubmed ID

28492159

DOI: Digital Object Identifier

040579197

Related Literature

SNS
PICO Info
in preparation
Languages

English

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