Treatment of insomnia with tricyclic antidepressants: a meta-analysis of polysomnographic randomized controlled trials.

Author: DongMeixue, JiaShiyu, LiuYang, WeiYoudong, XuXiaomin

Paper Details 
Original Abstract of the Article :
BACKGROUND: Insomnia represents a significant public health burden worldwide. Antidepressants have often been the insomnia treatment of choice in recent decades. Some tricyclic antidepressants (TCAs) have been shown to improve sleep efficiency. OBJECTIVE: Assess the efficacy and safety of TCAs for ...See full text at original site
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引用元:
https://doi.org/10.1016/j.sleep.2017.03.007

データ提供:米国国立医学図書館(NLM)

Treatment of Insomnia with Tricyclic Antidepressants: A Meta-Analysis

This study explores the use of tricyclic antidepressants (TCAs) in treating insomnia, a common sleep disorder. The authors conducted a meta-analysis of randomized controlled trials (RCTs) to assess the efficacy and safety of TCAs in improving sleep efficiency. The study provides a comprehensive review of the available evidence, highlighting the potential benefits and risks associated with using TCAs for insomnia. The study's findings offer valuable insights for clinicians in considering the use of TCAs for insomnia, weighing the potential benefits against the potential risks.

Tricyclic Antidepressants for Insomnia: Efficacy and Safety

This meta-analysis of randomized controlled trials (RCTs) provides evidence for the efficacy of tricyclic antidepressants (TCAs) in treating insomnia. The study's findings demonstrate that TCAs can significantly improve total sleep time compared to placebo. However, the study also highlights the potential for somnolence as a side effect of TCA use. This research underscores the need for careful consideration of the risks and benefits associated with using TCAs for insomnia.

Navigating Sleep Disorders: The Role of Tricyclic Antidepressants

This study delves into the complexities of using tricyclic antidepressants (TCAs) for insomnia, a common sleep disorder. The study's findings highlight the potential efficacy of TCAs in improving sleep efficiency, but also underscore the potential for somnolence as a side effect. This research underscores the need for careful consideration of the risks and benefits associated with using TCAs for insomnia, offering valuable insights for clinicians in weighing these factors when making treatment decisions. Just as a camel navigates the shifting sands of the desert, individuals with insomnia can navigate the complexities of sleep disorders with the help of appropriate and safe treatment options.

Dr. Camel's Conclusion

This study serves as a reminder that the path to restful sleep is often filled with twists and turns, and that the use of tricyclic antidepressants (TCAs) for insomnia is a complex journey. While TCAs can offer benefits in improving sleep efficiency, the potential for somnolence as a side effect demands careful consideration. This research encourages a mindful approach to using TCAs for insomnia, weighing the potential benefits against the potential risks, just as a camel navigates the desert with caution and wisdom.

Date :
  1. Date Completed 2018-03-07
  2. Date Revised 2018-03-07
Further Info :

Pubmed ID

28522080

DOI: Digital Object Identifier

10.1016/j.sleep.2017.03.007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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