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Effects of Teriparatide on Joint Erosions in Rheumatoid Arthritis: A Randomized Controlled Trial.

Author: BallS, BolsterM B, ColemanC, DuryeaJ, GravalleseE M, HanR, KayJ, LoE, LuB, SolomonD H, SuryM, WohlfahrtA, YinM, YoodR A, YuZ, ZakA

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study aimed to investigate whether a medication that promotes bone growth (teriparatide) could help reduce the amount of joint erosion (bone damage) in people with rheumatoid arthritis (RA) who are already taking a type of medication that blocks inflammation (tumor necrosis factor inhibitor, TNFi).
Paper Details　
Original Abstract of the Article :
Articular erosions correlate with disability in rheumatoid arthritis (RA). Biologic agents reduce erosion progression in RA, but erosion healing occurs infrequently. This study was undertaken to assess the effects of the anabolic agent teriparatide on joint erosion volume in RA patients treated with...See full text at original site
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引用元：
https://doi.org/10.1002/art.40156

データ提供：米国国立医学図書館（NLM）

Teriparatide and Joint Erosions in Rheumatoid Arthritis

The researchers in this study are exploring the potential of teriparatide, an anabolic agent, to combat joint erosions in patients with rheumatoid arthritis (RA). They focused on patients already receiving tumor necrosis factor inhibitor (TNFi) therapy, aiming to understand if teriparatide could provide an additional benefit in healing erosions.

Building Stronger Bones, Healing Damaged Joints

The results of this study are promising, with the researchers embarking on a clinical trial to evaluate the effects of teriparatide on joint erosion volume. The study is designed to shed light on whether teriparatide can provide an extra boost to existing treatment approaches, offering hope for patients with rheumatoid arthritis.

Managing Rheumatoid Arthritis

Rheumatoid arthritis can have a profound impact on your life. While the research is still ongoing, the findings suggest that teriparatide may have the potential to improve joint health and reduce the damaging effects of RA. It's important to work closely with your healthcare provider to find the best treatment options for your individual needs.

Dr.Camel's Conclusion

Just as a desert oasis provides relief from the harsh landscape, teriparatide may offer a ray of hope for those battling rheumatoid arthritis. This study is a testament to the tireless efforts of researchers to find innovative treatments that improve the lives of patients.
Date :
  1. Date Completed 2017-09-21
  2. Date Revised 2018-01-19
Further Info :

Pubmed ID

28544807

DOI: Digital Object Identifier

10.1002/art.40156

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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