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Intravenous nizatidine kinetics and acid suppression.

Author: BergstromR F, CallaghanJ T, KingE P, ObermeyerB D, OffenW W

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Intravenous nizatidine effectively suppressed gastric acid secretion in a dose-dependent manner. Nizatidine (100 mg) was comparable to cimetidine (300 mg) in its suppressive effects. The drug demonstrated linear pharmacokinetics.
Paper Details　
Original Abstract of the Article :
The effectiveness of intravenous nizatidine in suppressing gastric acid secretion was evaluated by different methods of inducing secretion in two single-blind studies. In study 1, seven subjects were given single, 20-min intravenous infusions of nizatidine (6.25, 25, 75, 150, or 250 mg) before modif...See full text at original site
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引用元：
https://doi.org/10.1038/clpt.1985.29

データ提供：米国国立医学図書館（NLM）

Nizatidine: A Powerful Weapon Against Gastric Acid

The human stomach is a fascinating organ, capable of churning out a potent cocktail of acids. Excessive gastric acid production can lead to heartburn and other digestive issues. This study investigates the effectiveness of nizatidine, a medication designed to suppress the production of gastric acid, in reducing the fiery wrath of our internal alchemists.

Nizatidine's Acid-Neutralizing Capabilities

The research, conducted in two separate studies, demonstrated that nizatidine effectively suppresses gastric acid secretion in a dose-dependent manner. The study's findings reveal a clear relationship between the dose of nizatidine administered and its ability to subdue the stomach's acidic fury.

Nizatidine: A Boon for Digestive Health

The research highlights nizatidine's potential to alleviate symptoms associated with excessive gastric acid production. This finding offers hope for individuals seeking relief from heartburn, indigestion, and other digestive ailments.

Dr.Camel's Conclusion

Nizatidine emerges as a promising tool in the fight against gastric acid, providing relief from the fiery torment of digestive issues. This research underscores the potential of this medication to improve the lives of individuals battling with excessive acid production.

Date :
  1. Date Completed 1985-03-15
  2. Date Revised 2019-05-10
Further Info :

Pubmed ID

2857117

DOI: Digital Object Identifier

10.1038/clpt.1985.29

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SNS
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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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