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Tolerability of combined treatment with verapamil and beta-blockers in angina resistant to monotherapy.

Author: McGourtyJ C, SilasJ H, SolomonS A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Combining verapamil with a beta-blocker was effective in treating angina refractory to either agent alone. While the combination showed promise, close monitoring is necessary due to potential side effects, limiting its use to hospital settings.
Paper Details　
Original Abstract of the Article :
We have used a combination of a beta-blocker and verapamil to treat 42 consecutive patients with angina resistant to either agent alone. Patients with heart failure, heart block or uncontrolled hypertension were excluded. The mean duration of follow-up was 6.5 months. Thirty-six patients (81%) repor...See full text at original site
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引用元：
https://doi.org/10.1136/pgmj.61.713.229

データ提供：米国国立医学図書館（NLM）

A Novel Approach to Treating Resistant Angina

Angina, a type of chest pain caused by reduced blood flow to the heart, can be a frustrating condition for patients. This study delves into the realm of cardiovascular medicine, exploring the effectiveness of a combined approach to treating angina that has resisted treatment with single medications. The authors investigated the use of a beta-blocker and verapamil together in patients whose angina had not responded to either medication alone. Their findings suggest that this combination therapy may be a viable option for a relatively broad range of patients struggling with difficult angina.

Unlocking the Potential of Combination Therapy

The study reports that 81% of the patients experienced improvement in their angina symptoms, highlighting the potential benefits of combining these two medications. However, it's crucial to acknowledge that this combination therapy may require careful dosage adjustments and close monitoring to minimize potential side effects.

A Balanced Approach to Angina Treatment

This research points to the value of carefully considering combination therapies for patients with resistant conditions. The authors emphasize the importance of a personalized approach to treatment, taking into account individual patient needs and potential side effects.

Dr.Camel's Conclusion

The search for effective treatments for resistant angina is an ongoing journey, and this study offers a promising avenue for exploration. While combination therapy can be a powerful tool, it is crucial to proceed with caution and personalized care to ensure the best possible outcomes for each patient.

Date :
  1. Date Completed 1985-05-09
  2. Date Revised 2019-05-01
Further Info :

Pubmed ID

2858847

DOI: Digital Object Identifier

10.1136/pgmj.61.713.229

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English

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