Paper Details 
Original Abstract of the Article :
Label="BACKGROUND" NlmCategory="BACKGROUND">Orodispersible tablets or fast dissolving tablets dissolve or disintegrate immediately on the patients' tongue or buccal mucosa. This drug delivery system is suitable for drugs undergoing high first pass metabolism. It improves bioavailability, reduces dos...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481693/

データ提供:米国国立医学図書館(NLM)

Orodispersible Tablets: A Novel Approach to Drug Delivery

The field of drug delivery is constantly evolving, seeking innovative ways to enhance medication effectiveness and patient experience. This study explores the potential of orodispersible tablets, which dissolve rapidly in the mouth, as a novel approach to delivering valsartan, an antihypertensive medication. The researchers investigated the use of a natural polysaccharide, isolated from Cassia tora seeds, as a superdisintegrant in these tablets.

Harnessing the Power of Natural Polysaccharides for Drug Delivery

The researchers, like desert explorers seeking out hidden treasures, investigated the use of a natural polysaccharide as a superdisintegrant, aiming to improve the dissolution rate and bioavailability of valsartan. Their findings revealed that this polysaccharide effectively promoted the rapid disintegration of the tablets, leading to quicker drug absorption and potentially improved therapeutic outcomes.

Potential Benefits of Orodispersible Tablets

This study highlights the potential benefits of orodispersible tablets, offering a convenient and patient-friendly drug delivery system. The rapid disintegration and absorption of the medication could lead to improved bioavailability, reduced dosing frequency, and minimized side effects. This innovative approach, like a refreshing oasis in a desert landscape, could enhance the overall patient experience while improving drug efficacy.

Dr.Camel's Conclusion

Orodispersible tablets, like a desert oasis offering a welcome respite, represent a promising innovation in drug delivery. This study's findings encourage further research into the use of natural polysaccharides as superdisintegrants to optimize drug delivery and improve patient outcomes.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-11-12
Further Info :

Pubmed ID

28664083

DOI: Digital Object Identifier

PMC5481693

Related Literature

SNS
PICO Info
in preparation
Languages

English

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