Effects of Benazepril on Survival of Dogs with Chronic Kidney Disease: A Multicenter, Randomized, Blinded, Placebo-Controlled Clinical Trial.

Author: AshR A, BonfantiU, BrovidaC, CroweI D, FontA, KingJ N, LanoreD, PechereauD, RousselotJ-F, SeewaldW, StrehlauG

Paper Details 
Original Abstract of the Article :
BACKGROUND: Chronic kidney disease (CKD) is an important cause of morbidity and mortality in dogs. OBJECTIVE: To evaluate the efficacy in prolonging survival and safety of benazepril administration to dogs with CKD. ANIMALS: Forty-nine client-owned dogs with CKD. METHODS: Dogs were randomized to ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508345/

データ提供:米国国立医学図書館(NLM)

Benazepril and Canine Chronic Kidney Disease: Exploring the Potential for Survival Benefit

Chronic kidney disease (CKD), a debilitating condition that affects millions of people and animals worldwide, is like a desert oasis slowly drying up, threatening to extinguish the life it sustains. This study investigates the potential of benazepril, an ACE inhibitor, to improve survival in dogs with CKD. The researchers, like dedicated desert healers, sought to find a way to slow the progression of this devastating disease.

Benazepril’s Impact on Canine CKD: A Randomized Clinical Trial

This study, like a well-planned expedition across a vast desert, conducted a randomized clinical trial to assess the effects of benazepril on survival in dogs with CKD. While the study found no significant survival benefit of benazepril compared to placebo, it did reveal a significant reduction in proteinuria, highlighting the potential for benazepril to manage a key symptom associated with CKD. This research, like a careful observation of the desert’s changing landscape, provides valuable insights into the potential of benazepril to manage CKD in dogs.

A Journey Through the Desert of Kidney Disease: Navigating Challenges and Finding Solutions

This research, like a compass guiding us through the desert of kidney disease, offers valuable insights into the complexities of managing CKD in dogs. While the study did not find a survival benefit of benazepril, it revealed a significant reduction in proteinuria, suggesting a potential role for benazepril in managing a key symptom of the disease. This research, like a testament to the resilience of life in harsh environments, highlights the ongoing quest for effective treatments and management strategies for CKD.

Dr.Camel's Conclusion

This study, like a tireless desert traveler searching for a hidden oasis, explores the potential of benazepril to improve survival in dogs with CKD. While the study did not find a significant survival benefit, it revealed a potential role for benazepril in managing proteinuria, highlighting the importance of ongoing research to develop effective treatments for this debilitating disease.

Date :
  1. Date Completed 2018-01-03
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28669137

DOI: Digital Object Identifier

PMC5508345

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Languages

English

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