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Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery).

Author: GoodPhillip, HardyJanet R, HaywoodAlison, KhanSohil, RickettKirsty, Vayne-BossertPetra

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Nausea is a common symptom in people with advanced cancer, affecting up to 70% of patients. While nausea can be caused by treatments like chemotherapy, radiation, or surgery, a significant number of people experience nausea unrelated to these treatments. Nausea can cause emotional distress and worsen quality of life for cancer patients. While corticosteroids are commonly used for nausea, their exact mechanism for relieving nausea is unknown. They also have potential side effects. Despite widespread use, there is limited evidence on how effective they are for nausea not related to cancer treatment. Further research is needed to understand their effects and determine if there are better options.
Paper Details　
Original Abstract of the Article :
Nausea is a common symptom in advanced cancer, with a prevalence of up to 70%. While nausea and vomiting can be related to cancer treatments, such as chemotherapy, radiotherapy, or surgery, a significant number of people with advanced cancer also suffer from nausea unrelated to such therapies. Nause...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379017/

データ提供：米国国立医学図書館（NLM）

Nausea in Advanced Cancer: A Silent Struggle

The experience of [advanced cancer] is often accompanied by a variety of challenging symptoms, including [nausea and vomiting]. This review article explores the use of [corticosteroids] in managing [nausea and vomiting] in patients with advanced cancer who are not experiencing these symptoms as a result of [chemotherapy, radiotherapy, or surgery]. The authors discuss the lack of clear evidence for the effectiveness of corticosteroids in this context and highlight the need for further research.

The authors acknowledge the widespread use of corticosteroids in [palliative care] for various non-specific indications, but they emphasize the need for objective evidence to support their use for managing nausea and vomiting in patients with advanced cancer. They also caution about the potential for [adverse effects] associated with corticosteroid use, which can vary depending on the dose and duration of treatment.

Understanding Nausea in Advanced Cancer

This review highlights the significant burden of nausea and vomiting experienced by patients with advanced cancer. It underscores the need for effective symptom management to improve quality of life and well-being. Further research is needed to determine the efficacy and safety of corticosteroids in this population.

Seeking Evidence-Based Approaches

This research emphasizes the importance of evidence-based medicine and the need to critically evaluate the effectiveness of commonly used interventions. Healthcare professionals should prioritize the use of treatments supported by strong evidence to ensure optimal patient care and minimize potential risks.

Dr.Camel's Conclusion

Nausea in advanced cancer is like a desert sandstorm, swirling with discomfort and distress. While corticosteroids might seem like a temporary oasis, we need more reliable evidence to navigate this challenging landscape and offer effective solutions to our patients.

Date :
  1. Date Completed 2017-09-08
  2. Date Revised 2020-02-25
Further Info :

Pubmed ID

28671265

DOI: Digital Object Identifier

PMC6379017

Related Literature

Article Analysis
・Effective treatment of nausea
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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