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A novel composite formulation of palmitoylethanolamide and quercetin decreases inflammation and relieves pain in inflammatory and osteoarthritic pain models.
Author: BrittiDomenico, CrupiRosalia, CuzzocreaSalvatore, Di PaolaRosanna, EvangelistaMaurizio, FuscoRoberta, GugliandoloEnrico, ImpellizzeriDaniela, MorittuValeria Maria, SchievanoCarlo
Original Abstract of the Article :
Osteoarthritis (OA) is a common progressive joint disease in dogs and cats. The goal of OA treatment is to reduce inflammation, minimize pain, and maintain joint function. Currently, non-steroidal anti-inflammatory drugs (e.g., meloxicam) are the cornerstone of treatment for OA pain, but side effect...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541643/
データ提供:米国国立医学図書館(NLM)
Palmitoylethanolamide and Quercetin: A New Oasis in the Desert of Osteoarthritis Pain
Osteoarthritis (OA), a degenerative joint disease, can cause significant pain and inflammation in dogs and cats. This study explores the potential of a novel composite formulation combining palmitoylethanolamide (PEA) and quercetin for treating OA pain. The researchers tested the formulation in two rat models of inflammatory and OA pain: carrageenan paw edema and sodium monoiodoacetate (MIA)-induced OA. The results demonstrate that the composite formulation, administered orally, significantly reduced inflammation and relieved pain in both models, comparable to meloxicam, a commonly used NSAID. These findings suggest that the combination of PEA and quercetin holds promise as a potential alternative or complementary treatment for OA pain, offering a potentially safer and more effective approach.
A New Path in the Desert of OA Treatment
This study offers a promising new path in the desert of OA treatment, showcasing the potential benefits of combining PEA and quercetin. The researchers' findings suggest that this novel formulation could provide a safe and effective alternative or complementary treatment for OA pain. This discovery could lead to new therapeutic options for both animals and humans suffering from OA, offering a potential oasis of relief in the midst of chronic pain. It's like finding a new source of water in the desert, providing a refreshing alternative for those seeking a solution to their pain.
Finding Relief in the Desert of Pain
This study provides hope for individuals seeking relief from OA pain. The researchers' findings demonstrate the potential of a novel PEA-quercetin composite formulation to reduce inflammation and alleviate pain, offering a potentially safer and more effective alternative to traditional NSAIDs. It's like finding a hidden oasis in the desert of pain, offering a soothing respite from the harsh realities of OA. By exploring innovative treatment strategies, researchers are paving the way for a more comfortable and fulfilling life for individuals living with OA.
Dr.Camel's Conclusion
This study offers promising insights into the potential of a novel PEA-quercetin composite formulation for treating OA pain. Its effectiveness and safety make it a potential game-changer in the desert of OA treatment, offering a refreshing alternative for those seeking relief from chronic pain.
Date :
- Date Completed 2018-04-02
- Date Revised 2020-12-09
Further Info :
Related Literature
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