Paper Details

  1. Home
  2. Paper Details

The current therapeutic options for Crohn's disease: from medical therapy to intestinal transplantation.

Author: D'AmicoFrancesco, GondolesiGabriel, LauroAugusto

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Crohn's disease (CD) is a chronic condition affecting the intestines. While medications and nutritional support are the main treatments, over half of patients need surgery to remove part of the intestine. This often needs to be repeated over time, and some people develop short bowel syndrome, requiring intravenous feeding. Intestinal transplantation (ITx) can be an option for people with severe intestinal problems, with a survival rate of 79% at one year, 53% at three years, and 43% at five years. This review examines the medical, endoscopic, surgical, and transplant options for managing CD.
Paper Details　
Original Abstract of the Article :
Label="INTRODUCTION" NlmCategory="BACKGROUND">Crohn's disease (CD) has an annual incidence per 100.000 person-year of 20.2 in North America and 12.7 in Europe, and the purpose of this review is to evaluate its medical management, from diagnosis to transplant. Pharmacologic manipulation with nutritio...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1080/17474124.2017.1367665

データ提供：米国国立医学図書館（NLM）

Crohn's Disease: Navigating a Desert of Challenges

Crohn's disease (CD), a chronic inflammatory bowel disorder, presents a complex landscape of challenges for patients and clinicians alike. This study examines the current therapeutic options for CD, encompassing medical therapy, surgery, and intestinal transplantation.

The study emphasizes the importance of a multidisciplinary approach to managing CD. While pharmacologic manipulation and nutritional care are the cornerstones of treatment, more than half of patients require intestinal resection. Intestinal transplantation, like a new oasis, emerges as an alternative for patients with irreversible intestinal failure and life-threatening complications.

A New Oasis in the Desert of Crohn's Disease: Intestinal Transplantation

The study highlights the critical role of intestinal transplantation in managing severe CD. It provides valuable insights into the long-term survival rates and potential benefits of this complex procedure. The study underscores the importance of ongoing research and advancements in transplantation techniques to improve outcomes for patients with CD.

Navigating the Desert of Crohn's Disease: Understanding the Options

This study serves as a valuable guide for patients and clinicians navigating the complexities of CD. It provides a comprehensive overview of therapeutic options, including medical management, surgery, and intestinal transplantation. The study highlights the importance of individualized care and the need for ongoing dialogue between patients and healthcare providers to develop the most appropriate management plan.

Dr. Camel's Conclusion

The study underscores the multifaceted nature of managing Crohn's disease, emphasizing the importance of a personalized approach that considers medical therapy, surgery, and intestinal transplantation. The study provides valuable insights into the potential benefits and limitations of each therapeutic option, guiding clinicians in providing optimal care for their patients.
Date :
  1. Date Completed 2018-10-03
  2. Date Revised 2018-12-02
Further Info :

Pubmed ID

28805088

DOI: Digital Object Identifier

10.1080/17474124.2017.1367665

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.