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Neuropsychiatric adverse drug reactions in children initiated on montelukast in real-life practice.

Author: BastienValérie, BenardBrigitte, DucharmeFrancine M, KrajinovicMaja, VinetBenjamin, YangRoger

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Montelukast is a medication used to treat asthma. While it is generally safe, it has been linked to serious side effects involving the brain and mental state. This study looked at how often children who took montelukast had to stop taking the medication because of these side effects.
Paper Details　
Original Abstract of the Article :
Although montelukast is generally well tolerated, postmarketing studies have reported serious neuropsychiatric adverse drug reactions (ADRs) leading to a United States Food and Drug Administration black box warning. The objective of this study was to determine the incidence of neuropsychiatric ADRs ...See full text at original site
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引用元：
https://doi.org/10.1183/13993003.00148-2017

データ提供：米国国立医学図書館（NLM）

Neuropsychiatric Adverse Drug Reactions in Children Initiated on Montelukast in Real-Life Practice

The world of pediatric medicine is a delicate one, requiring careful consideration of the potential risks and benefits of treatments. This research explores the potential neuropsychiatric side effects of montelukast, a commonly prescribed medication for asthma, in children. The study aimed to determine the incidence of neuropsychiatric adverse drug reactions (ADRs) leading to discontinuation of montelukast in asthmatic children. The researchers conducted a retrospective cohort study, examining the records of children who had been prescribed montelukast.

A Hidden Oasis in the Desert of Pediatric Asthma Treatment

The study found that a notable number of children experienced neuropsychiatric ADRs, leading to discontinuation of montelukast. The most common ADRs were irritability, aggressiveness, and sleep disturbances. It's like finding a hidden oasis in the desert of pediatric asthma treatment, but one that requires careful navigation to avoid potential adverse effects.

Navigating the Desert of Pediatric Asthma Treatment

This research highlights the importance of monitoring for potential neuropsychiatric side effects in children taking montelukast. It's like finding a path through the desert, requiring careful observation and adjustments along the way. The study emphasizes the importance of close communication between parents, patients, and healthcare professionals to ensure safe and effective asthma management.

Dr. Camel's Conclusion

This research provides a valuable reminder that even seemingly safe medications can have unforeseen side effects. It's like navigating a vast desert landscape, where potential hazards can be lurking in the shadows. The study underscores the importance of careful monitoring and open communication between healthcare providers and families to ensure the well-being of children with asthma.

Date :
  1. Date Completed 2018-05-17
  2. Date Revised 2021-12-04
Further Info :

Pubmed ID

28818882

DOI: Digital Object Identifier

10.1183/13993003.00148-2017

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Article Analysis
・Side Effects of montelukast
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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