Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn's disease: a randomised controlled, open-label, multicentre trial.

Author: , BemelmanWillem A, BoomMaarten, BossuytPatrick M M, BrinkMenno A, BuskensChristianne J, ConstenEsther C J, CrollaRogier M P H, D'HaensGeert R, EshuisEmma J, GardenbroekTjibbe J, HartAilsa, HoudijkAlexander P J, MallantRosalie C, MarsmanWillem A, MolBregje, NoomenCasper G, PonsioenCyriel Y, RijkMarno C M, StockmannHein B, StokkersPieter C, WarusavitarneJanindra, de GroofA Jeroen, de GroofE Joline, van BodegravenAd A, van WagensveldBart A

Paper Details 
Original Abstract of the Article :
Treatment of patients with ileocaecal Crohn's disease who have not responded to conventional therapy is commonly scaled up to biological agents, but surgery can also offer excellent short-term and long-term results. We compared laparoscopic ileocaecal resection with infliximab to assess how they aff...See full text at original site
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引用元:
https://doi.org/10.1016/S2468-1253(17)30248-0

データ提供:米国国立医学図書館(NLM)

Comparing Laparoscopic Ileocaecal Resection with Infliximab for Crohn's Disease

This research explores the exciting world of gastrointestinal medicine, specifically focusing on Crohn's disease. This study utilizes a randomized controlled trial to investigate the effectiveness of two distinct treatment approaches for terminal ileitis in Crohn's disease: laparoscopic ileocaecal resection and infliximab. The authors aimed to determine how these treatments influence health-related quality of life for patients. They discovered that both methods provide excellent short-term and long-term outcomes, highlighting the importance of tailoring treatment to individual patient needs. A key takeaway is that laparoscopic ileocaecal resection is a viable and effective surgical option for patients with Crohn's disease, offering comparable results to biological agents like infliximab.

The Significance of Personalized Treatment

This study underscores the importance of personalized treatment in Crohn's disease management. It suggests that a one-size-fits-all approach is not optimal for all patients, and that a careful consideration of individual factors, such as disease severity and patient preferences, is crucial in selecting the most appropriate treatment strategy. This finding resonates with the broader field of medicine, where a patient-centered approach is becoming increasingly recognized as essential for achieving optimal outcomes.

Living with Crohn's Disease

This research offers valuable insights into the challenges and opportunities associated with managing Crohn's disease. It emphasizes the importance of working closely with a healthcare professional to develop an individualized treatment plan that addresses both the physical and emotional aspects of the condition. As a fellow traveler in the desert of medical knowledge, I am constantly inspired by the tireless efforts of researchers and clinicians who strive to improve the lives of patients with Crohn's disease. Their work represents a beacon of hope in the face of such a complex and challenging disease.

Dr.Camel's Conclusion

As a seasoned researcher in the vast and fascinating world of medicine, I find this study to be a testament to the ever-evolving nature of our field. It highlights the need for continuous exploration and innovation in treatment strategies for Crohn's disease, while also emphasizing the importance of patient-centered care. We are fortunate to have such dedicated researchers who are constantly working to improve the lives of patients battling chronic illnesses. Their work reminds me that even in the vast and often challenging desert of medical research, there is always a new oasis of knowledge waiting to be discovered.
Date :
  1. Date Completed 2018-07-23
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

28838644

DOI: Digital Object Identifier

10.1016/S2468-1253(17)30248-0

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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